Mm00431822_m1

• Gene Symbol: App
• Gene Name: amyloid beta (A4) precursor protein
• Gene Aliases: Abeta, Abpp, Adap, Ag, Cvap, E030013M08Rik, betaApp
• Chromosome Location: Chr.16: 84954436 - 85173952 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: App
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001198823.1	NP_001185752.1	4 - 5	619		88
	NM_001198824.1	NP_001185753.1	4 - 5	619		88
	NM_001198825.1	NP_001185754.1	4 - 5	619		88
	NM_001198826.1	NP_001185755.1	4 - 5	619		88
	NM_007471.3	NP_031497.2	4 - 5	619		88
GenBank mRNA	AK133639.1	-	4 - 5	616		88
	AK147543.1	-	4 - 5	655		88
	AK148439.1	-	4 - 5	491		88
	AK159352.1	-	4 - 5	626		88
	AK159718.1	-	4 - 5	605		88
	AY267348.1	-	4 - 5	470		88
	BC070409.1	-	4 - 5	615	5708093	88
	M18373.1	-	4 - 5	608		88
	U84012.1	-	4 - 5	608		88

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1600001966.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene App

Gene Ontology Categories:

Process(es)

suckling behavior
mRNA polyadenylation
regulation of translation
protein phosphorylation
cellular copper ion homeostasis
endocytosis
apoptotic process
response to oxidative stress
cell adhesion
regulation of epidermal growth factor-activated receptor activity
Notch signaling pathway
nervous system development
axonogenesis
mating behavior
locomotory behavior
axo-dendritic transport
cholesterol metabolic process
adult locomotory behavior
visual learning
negative regulation of peptidase activity
regulation of gene expression
negative regulation of endopeptidase activity
positive regulation of peptidase activity
positive regulation of G2/M transition of mitotic cell cycle
axon midline choice point recognition
neuron remodeling
dendrite development
extracellular matrix organization
forebrain development
neuron projection development
ionotropic glutamate receptor signaling pathway
regulation of multicellular organism growth
regulation of protein binding
negative regulation of neuron differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription by RNA polymerase II
collateral sprouting in absence of injury
regulation of synapse structure or activity
neuromuscular process controlling balance
synaptic assembly at neuromuscular junction
protein homooligomerization
neuron apoptotic process
smooth endoplasmic reticulum calcium ion homeostasis

Function(s)

DNA binding
serine-type endopeptidase inhibitor activity
signaling receptor binding
protein binding
heparin binding
peptidase activator activity
enzyme binding
peptidase inhibitor activity
acetylcholine receptor binding
identical protein binding
metal ion binding
transition metal ion binding
PTB domain binding
growth factor receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	TC1600001966.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_001198823.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_001198823.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_001198824.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_001198824.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_001198825.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_001198825.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_001198826.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_001198826.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_007471.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015246.mm.1	NM_007471.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	TC1600001966.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_001198823.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_001198823.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_001198824.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_001198824.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_001198825.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_001198825.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_001198826.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_001198826.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_007471.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015245.mm.1	NM_007471.3	Refseq