Mm00431827_m1

• Gene Symbol: App
• Gene Name: amyloid beta (A4) precursor protein
• Gene Aliases: Abeta, Abpp, Adap, Ag, Cvap, E030013M08Rik, betaApp
• Chromosome Location: Chr.16: 84954436 - 85173952 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: App
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001198823.1	NP_001185752.1	11 - 12	1605		130
	NM_001198824.1	NP_001185753.1	10 - 11	1548		130
	NM_001198825.1	NP_001185754.1	10 - 11	1548		130
	NM_001198826.1	NP_001185755.1	11 - 12	1605		130
	NM_007471.3	NP_031497.2	9 - 10	1380		130
GenBank mRNA	AK029172.1	-	1 - 2	2773		130
	AK076506.1	-	3 - 4	300		130
	AK128971.1	-	10 - 11	1557		130
	AK133639.1	-	10 - 11	1545		130
	AK147543.1	-	9 - 10	1416		130
	AK148439.1	-	11 - 12	1478		130
	AK159245.1	-	11 - 12	1614		130
	AK159352.1	-	11 - 12	1611		130
	AK159718.1	-	11 - 12	1591		130
	AK161854.1	-	4 - 5	462		130
	AK161976.1	-	9 - 10	1355		130
	AY267348.1	-	11 - 12	1456		130
	BC005490.1	-	7 - 8	969		130
	BC070409.1	-	9 - 10	1376	5708093	130
	M18373.1	-	9 - 10	1369		130
	U84012.1	-	9 - 10	1369		130
	X59379.1	-	9 - 10	1299		130

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1600001966.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, Mouse Hypoxia Panel, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene App

Gene Ontology Categories:

Process(es)

suckling behavior
mRNA polyadenylation
regulation of translation
protein phosphorylation
cellular copper ion homeostasis
endocytosis
apoptotic process
response to oxidative stress
cell adhesion
regulation of epidermal growth factor-activated receptor activity
Notch signaling pathway
nervous system development
axonogenesis
mating behavior
locomotory behavior
axo-dendritic transport
cholesterol metabolic process
adult locomotory behavior
visual learning
negative regulation of peptidase activity
regulation of gene expression
negative regulation of endopeptidase activity
positive regulation of peptidase activity
positive regulation of G2/M transition of mitotic cell cycle
axon midline choice point recognition
neuron remodeling
dendrite development
extracellular matrix organization
forebrain development
neuron projection development
ionotropic glutamate receptor signaling pathway
regulation of multicellular organism growth
regulation of protein binding
negative regulation of neuron differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription by RNA polymerase II
collateral sprouting in absence of injury
regulation of synapse structure or activity
neuromuscular process controlling balance
synaptic assembly at neuromuscular junction
protein homooligomerization
neuron apoptotic process
smooth endoplasmic reticulum calcium ion homeostasis

Function(s)

DNA binding
serine-type endopeptidase inhibitor activity
signaling receptor binding
protein binding
heparin binding
peptidase activator activity
enzyme binding
peptidase inhibitor activity
acetylcholine receptor binding
identical protein binding
metal ion binding
transition metal ion binding
PTB domain binding
growth factor receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	TC1600001966.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_001198823.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_001198823.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_001198824.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_001198824.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_001198825.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_001198825.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_001198826.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_001198826.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_007471.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600015239.mm.1	NM_007471.3	Refseq

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	856449	-	-