Mm00433207_m1

• Gene Symbol: Ptk2
• Gene Name: PTK2 protein tyrosine kinase 2
• Gene Aliases: FAK, FRNK, Fadk, mKIAA4203, p125FAK
• Chromosome Location: Chr.15: 73205102 - 73423275 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ptk2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001130409.1	NP_001123881.1	20 - 21	2105		77
	NM_007982.2	NP_032008.2	19 - 20	1950		77
GenBank mRNA	AB011499.1	-	20 - 21	1761		77
	AB030035.1	-	18 - 19	1576		77
	AK079821.1	-	20 - 21	2202		77
	AK220543.1	-	19 - 20	1950		77
	BC030180.1	-	20 - 21	2035		77
	JN971016.1	-	19 - 20	1677		77
	M95408.1	-	18 - 19	1747		77

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1500001690.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ptk2

Gene Ontology Categories:

Process(es)

MAPK cascade
microtubule cytoskeleton organization
angiogenesis
blood vessel development
vasculogenesis
neuron migration
regulation of protein phosphorylation
positive regulation of protein phosphorylation
protein phosphorylation
movement of cell or subcellular component
cell adhesion
signal complex assembly
epidermal growth factor receptor signaling pathway
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
JNK cascade
multicellular organism development
positive regulation of cell proliferation
regulation of cell shape
regulation of epithelial cell migration
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of smooth muscle cell migration
phosphorylation
peptidyl-tyrosine phosphorylation
central nervous system neuron axonogenesis
negative regulation of cell-cell adhesion
regulation of cell adhesion
extracellular matrix organization
positive regulation of cell growth
positive regulation of cell migration
negative regulation of cell migration
cellular chloride ion homeostasis
regulation of cell adhesion mediated by integrin
peptidyl-tyrosine autophosphorylation
establishment of nucleus localization
regulation of cell proliferation
negative regulation of apoptotic process
endothelial cell migration
innate immune response
regulation of osteoblast differentiation
positive regulation of cell adhesion
positive regulation of protein kinase activity
positive regulation of vasodilation
negative regulation of organ growth
protein autophosphorylation
ephrin receptor signaling pathway
positive regulation of smooth muscle cell proliferation
positive regulation of phagocytosis
negative regulation of axonogenesis
positive regulation of synaptic transmission
regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
negative regulation of synapse assembly
positive regulation of glial cell proliferation
growth hormone receptor signaling pathway
cellular response to transforming growth factor beta stimulus
regulation of substrate adhesion-dependent cell spreading
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of anoikis

Function(s)

nucleotide binding
actin binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
signal transducer activity
receptor binding
integrin binding
protein binding
ATP binding
JUN kinase binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein complex binding
SH2 domain binding
identical protein binding
phosphatidylinositol 3-kinase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1500012758.mm.1	NM_001130409.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500012758.mm.1	NM_001130409.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500012758.mm.1	NM_007982.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500012758.mm.1	NM_007982.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1500012758.mm.1	TC1500001690.mm.1	MTA TC