Mm00434253_g1

• Gene Symbol: Irak1
• Gene Name: interleukin-1 receptor-associated kinase 1
• Gene Aliases: AA408924, IRAK, IRAK-1, IRAK1-S, Il1rak, Plpk, mPLK
• Chromosome Location: Chr.X: 74013914 - 74023921 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Irak1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001177973.1	NP_001171444.1	13 - 14	2214		93
	NM_001177974.1	NP_001171445.1	12 - 13	2094		93
	NM_001177975.1	NP_001171446.1	12 - 13	2094		93
	NM_001177976.1	NP_001171447.1	12 - 13	2094		93
	NM_008363.2	NP_032389.2	12 - 13	2094		93
GenBank mRNA	AB088370.1	-	12 - 13	1650		93
	AF103876.1	-	12 - 13	2094		93
	AK045958.1	-	12 - 13	2003		93
	AK052933.1	-	10 - 11	1964		93
	AK143694.1	-	12 - 13	2005		93
	AK144879.1	-	12 - 13	2003		93
	AY184362.1	-	12 - 13	2094		93
	AY184363.1	-	12 - 13	2094		93
	AY184364.1	-	12 - 13	2094		93
	BC004778.1	-	13 - 14	2206	3257579	93
	U56773.2	-	12 - 13	1918		93

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0X00002442.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, 3' Most, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Irak1

Gene Ontology Categories:

Process(es)

regulation of cytokine-mediated signaling pathway
immune system process
protein phosphorylation
signal transduction
activation of NF-kappaB-inducing kinase activity
JNK cascade
phosphorylation
cytokine-mediated signaling pathway
lipopolysaccharide-mediated signaling pathway
negative regulation of NF-kappaB transcription factor activity
response to peptidoglycan
response to lipopolysaccharide
toll-like receptor 2 signaling pathway
toll-like receptor 4 signaling pathway
cellular response to heat
intracellular signal transduction
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAP kinase activity
positive regulation of JUN kinase activity
innate immune response
negative regulation of transcription, DNA-templated
protein autophosphorylation
positive regulation of smooth muscle cell proliferation
positive regulation of NF-kappaB transcription factor activity
protein complex oligomerization
interleukin-1-mediated signaling pathway
response to interleukin-1
negative regulation of cholesterol efflux

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
interleukin-1 receptor binding
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
heat shock protein binding
protein homodimerization activity
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	TC0X00002442.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_001177973.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_001177973.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_001177974.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_001177974.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_001177975.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_001177975.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_001177976.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_001177976.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_008363.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015376.mm.1	NM_008363.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	TC0X00002442.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_001177973.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_001177973.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_001177974.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_001177974.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_001177975.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_001177975.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_001177976.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_001177976.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_008363.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0X00015377.mm.1	NM_008363.2	Refseq