Mm00434255_g1

• Gene Symbol: Il2
• Gene Name: interleukin 2
• Gene Aliases: Il-2
• Chromosome Location: Chr.3: 37120713 - 37125954 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Il2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008366.3	NP_032392.1	1 - 2	239		101
GenBank mRNA	AF065914.1	-	1 - 2	237		101
	AF065915.1	-	1 - 2	237		101
	AF065916.1	-	1 - 2	237		101
	AY147902.1	-	1 - 2	191		101
	BC116845.1	-	1 - 2	237	40126164	101
	BC116873.1	-	1 - 2	237	40126192	101
	DQ836354.1	-	1 - 2	131		101
	K02292.1	-	1 - 2	239		101
	U41494.1	-	1 - 2	134		101
	U41504.1	-	1 - 2	149		101
	U41505.1	-	1 - 2	161		101
	U41506.1	-	1 - 2	134		101
	X01772.1	-	1 - 2	238		101
	X73040.1	-	1 - 2	238		101

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0300001864.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Il2

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein, non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
immune system process
negative regulation of B cell apoptotic process
immune response
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
positive regulation of B cell proliferation
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
positive regulation of T cell proliferation
positive regulation of activated T cell proliferation
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of T cell differentiation
positive regulation of regulatory T cell differentiation
negative regulation of heart contraction
positive regulation of transcription from RNA polymerase II promoter
regulation of T cell homeostatic proliferation
positive regulation of isotype switching to IgG isotypes
negative regulation of lymphocyte proliferation
negative regulation of inflammatory response
positive regulation of immunoglobulin secretion
positive regulation of dendritic spine development
extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

cytokine activity
interleukin-2 receptor binding
growth factor activity
carbohydrate binding
kappa-type opioid receptor binding
glycosphingolipid binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0300014437.mm.1	NM_008366.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300014437.mm.1	NM_008366.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300014437.mm.1	TC0300001864.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300014439.mm.1	NM_008366.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300014439.mm.1	NM_008366.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300014439.mm.1	TC0300001864.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300014438.mm.1	NM_008366.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300014438.mm.1	NM_008366.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0300014438.mm.1	TC0300001864.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	926257	-	-