Mm00435424_m1

• Gene Symbol: Ntrk2
• Gene Name: neurotrophic tyrosine kinase, receptor, type 2
• Gene Aliases: GP145-TrkB/GP95-TrkB, Tkrb, trk-B, trkB
• Chromosome Location: Chr.13: 58806569 - 59133970 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ntrk2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001025074.2	NP_001020245.1	11 - 12	1954		74
	NM_001282961.1	NP_001269890.1	11 - 12	1921		74
	NM_008745.3	NP_032771.1	11 - 12	1921		74
GenBank mRNA	AB377224.1	-	10 - 11	1331		74
	AB377225.1	-	10 - 11	1331		74
	AK009606.1	-	10 - 11	1308		74
	AK018789.1	-	11 - 12	1852		74
	AK028827.1	-	11 - 12	1774		74
	AK147391.1	-	11 - 12	1752		74
	AK147441.1	-	10 - 11	1742		74
	AK160789.1	-	11 - 12	1922		74
	BC052014.1	-	10 - 11	1716	5707891	74
	M33385.1	-	10 - 11	1293		74
	X17647.1	-		1804		74

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1300000718.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ntrk2

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

vasculogenesis
neuron migration
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
neuromuscular junction development
learning
long-term memory
feeding behavior
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of neuron projection development
glutamate secretion
positive regulation of phosphatidylinositol 3-kinase signaling
phosphorylation
peptidyl-tyrosine phosphorylation
regulation of metabolic process
central nervous system neuron development
cerebral cortex development
cell differentiation
neuron differentiation
brain-derived neurotrophic factor receptor signaling pathway
positive regulation of peptidyl-serine phosphorylation
calcium-mediated signaling using intracellular calcium source
neurotrophin signaling pathway
mechanoreceptor differentiation
regulation of GTPase activity
regulation of MAPK cascade
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
retinal rod cell development
protein autophosphorylation
regulation of neurotransmitter secretion
oligodendrocyte differentiation
peripheral nervous system neuron development
positive regulation of axonogenesis
regulation of dendrite development
regulation of protein kinase B signaling
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
retina development in camera-type eye
long-term synaptic potentiation
cellular response to amino acid stimulus
positive regulation of glucocorticoid receptor signaling pathway
negative regulation of anoikis

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
neurotrophin receptor activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein homodimerization activity
neurotrophin binding
ephrin receptor binding
brain-derived neurotrophic factor binding
brain-derived neurotrophic factor-activated receptor activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1300004737.mm.1	NM_001025074.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1300004737.mm.1	NM_001282961.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1300004737.mm.1	NM_008745.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1300004737.mm.1	TC1300000718.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1300004743.mm.1	NM_001025074.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1300004743.mm.1	NM_001282961.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1300004743.mm.1	TC1300000718.mm.1	MTA TC