Mm00435831_m1

• Gene Symbol: Pkd2
• Gene Name: polycystic kidney disease 2
• Gene Aliases: C030034P18Rik, PC2, TRPP2
• Chromosome Location: Chr.5: 104457224 - 104505819 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pkd2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008861.3	NP_032887.3	3 - 4	1018		61
GenBank mRNA	AF014010.1	-	3 - 4	921		61
	AK053502.1	-	3 - 4	923		61
	AK128961.1	-	4 - 5	792		61
	AK164673.1	-	3 - 4	909		61
	BC053058.1	-	3 - 4	1025		61
	BC062969.1	-	3 - 4	1025		61
	FJ609779.1	-	3 - 4	934		61
	Y13278.1	-	3 - 4	934		61
	Y14120.1	-	3 - 4	684		61

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500001026.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pkd2

Gene Ontology Categories:

Process(es)

kidney development
liver development
embryonic placenta development
heart looping
detection of nodal flow
transport
ion transport
calcium ion transport
cellular calcium ion homeostasis
positive regulation of cytosolic calcium ion concentration
receptor signaling pathway via JAK-STAT
determination of left/right symmetry
heart development
positive regulation of gene expression
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
sodium ion transmembrane transport
regulation of cell population proliferation
cytoplasmic sequestering of transcription factor
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription by RNA polymerase II
detection of mechanical stimulus
release of sequestered calcium ion into cytosol
transmembrane transport
negative regulation of ryanodine-sensitive calcium-release channel activity
placenta blood vessel development
renal tubule morphogenesis
calcium ion transmembrane transport
cellular response to hydrostatic pressure
cellular response to osmotic stress
cellular response to fluid shear stress
potassium ion transmembrane transport
determination of liver left/right asymmetry
renal system development
regulation of calcium ion import
negative regulation of G1/S transition of mitotic cell cycle

Function(s)

signaling receptor binding
voltage-gated ion channel activity
voltage-gated calcium channel activity
voltage-gated sodium channel activity
calcium channel activity
potassium channel activity
calcium ion binding
protein binding
cytoskeletal protein binding
channel activity
voltage-gated cation channel activity
identical protein binding
protein homodimerization activity
actinin binding
HLH domain binding
transmembrane transporter binding
metal ion binding
calcium-induced calcium release activity
ATPase binding
phosphoprotein binding
muscle alpha-actinin binding
alpha-actinin binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500008667.mm.1	TC0500001026.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500008667.mm.1	NM_008861.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500008667.mm.1	NM_008861.3	Refseq