Mm00436360_m1

• Gene Symbol: Ripk1
• Gene Name: receptor (TNFRSF)-interacting serine-threonine kinase 1
• Gene Aliases: D330015H01Rik, RIP, Rinp, Rip1
• Chromosome Location: Chr.13: 34000844 - 34035170 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ripk1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_009068.3	NP_033094.3	8 - 9	1148		78
GenBank mRNA	AK030959.1	-	8 - 9	1379		78
	AK156803.1	-	8 - 9	1413		78
	BC050905.1	-	8 - 9	1148	5721177	78
	BC054542.1	-	8 - 9	1148	5721177	78
	BC058162.1	-	8 - 9	1334	5135235	78
	U25995.1	-	7 - 8	1063		78

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1300000384.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ripk1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
protein phosphorylation
apoptotic process
signal transduction
positive regulation of cell death
programmed cell death
viral process
phosphorylation
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
response to tumor necrosis factor
peptidyl-serine autophosphorylation
positive regulation of phosphorylation
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAPK cascade
cellular protein catabolic process
positive regulation of macrophage differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
protein heterooligomerization
positive regulation of transferase activity
positive regulation of necroptotic process
T cell apoptotic process
necroptotic process
regulation of ATP:ADP antiporter activity
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
extrinsic apoptotic signaling pathway
ripoptosome assembly
necroptotic signaling pathway
ripoptosome assembly involved in necroptotic process
amyloid fibril formation
regulation of reactive oxygen species metabolic process
negative regulation of extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
death receptor binding
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
ubiquitin protein ligase binding
protein complex binding
identical protein binding
death domain binding