Mm00437227_m1

• Gene Symbol: Axl
• Gene Name: AXL receptor tyrosine kinase
• Gene Aliases: AI323647, Ark, Tyro7, Ufo
• Chromosome Location: Chr.7: 25756500 - 25788733 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Axl
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001190974.1	NP_001177903.1	11 - 12	1747		86
	NM_001190975.1	NP_001177904.1	10 - 11	1483		86
	NM_009465.4	NP_033491.2	12 - 13	1774		86
GenBank mRNA	AK033237.1	-	11 - 12	1716		86
	AK155567.1	-	13 - 14	1660		86
	AK161294.1	-	5 - 6	447		86
	AK170010.1	-	11 - 12	1721		86
	AK170897.1	-	11 - 12	1380		86
	BC008551.1	-	7 - 8	864		86
	BC046618.1	-	12 - 13	1611	6494383	86
	BC050914.1	-	12 - 13	1582	6418252	86
	BC058230.1	-	12 - 13	1635	6313662	86
	X63535.1	-	12 - 13	1523		86

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0700002644.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Axl

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

neuron migration
natural killer cell differentiation
positive regulation of cytokine-mediated signaling pathway
blood vessel remodeling
immune system process
protein phosphorylation
phagocytosis
inflammatory response
enzyme linked receptor protein signaling pathway
spermatogenesis
phosphorylation
peptidyl-tyrosine phosphorylation
forebrain cell migration
cell differentiation
platelet activation
cellular response to extracellular stimulus
negative regulation of interferon-gamma production
negative regulation of tumor necrosis factor production
positive regulation of natural killer cell differentiation
secretion by cell
erythrocyte homeostasis
substrate adhesion-dependent cell spreading
cellular response to interferon-alpha
ovulation cycle
negative regulation of apoptotic process
apoptotic cell clearance
protein kinase B signaling
negative regulation of neuron apoptotic process
innate immune response
viral entry into host cell
positive regulation of pinocytosis
negative regulation of lymphocyte activation
positive regulation of protein kinase B signaling
vagina development
cellular response to hydrogen peroxide
cellular response to lipopolysaccharide
negative regulation of dendritic cell apoptotic process

Function(s)

nucleotide binding
phosphatidylserine binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
myosin heavy chain binding
phosphatidylinositol 3-kinase binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0700022898.mm.1	TC0700002644.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0700022898.mm.1	NM_001190974.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0700022898.mm.1	NM_001190974.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0700022898.mm.1	NM_001190975.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0700022898.mm.1	NM_001190975.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0700022898.mm.1	NM_009465.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0700022898.mm.1	NM_009465.4	Refseq