Mm00437431_m1

• Gene Symbol: Acvrl1
• Gene Name: activin A receptor, type II-like 1
• Gene Aliases: AI115505, AI427544, Acvrlk1, Alk1
• Chromosome Location: Chr.15: 101128522 - 101145336 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Acvrl1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001277255.1	NP_001264184.1	10 - 11	1540		57
	NM_001277257.1	NP_001264186.1	9 - 10	1479		57
	NM_001277258.1	NP_001264187.1	9 - 10	1448		57
	NM_001277259.1	NP_001264188.1	10 - 11	1535		57
	NM_009612.3	NP_033742.2	9 - 10	1517		57
GenBank mRNA	AK134712.1	-	7 - 8	1274		57
	AK160915.1	-	10 - 11	1508		57
	AK170870.1	-	7 - 8	1273		57
	BC015083.1	-	8 - 9	1398	3980151	57
	L48015.1	-	9 - 10	1519		57
	Z31664.1	-	9 - 10	1485		57

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1500001061.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Acvrl1

Panther Classification:

Molecular Function -

serine/threonine protein kinase receptor

Gene Ontology Categories:

Process(es)

angiogenesis
in utero embryonic development
negative regulation of endothelial cell proliferation
positive regulation of endothelial cell proliferation
lymphangiogenesis
blood vessel remodeling
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of cell adhesion
signal transduction
transmembrane receptor protein serine/threonine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
blood circulation
regulation of blood pressure
negative regulation of cell proliferation
negative regulation of endothelial cell migration
positive regulation of pathway-restricted SMAD protein phosphorylation
phosphorylation
signal transduction by protein phosphorylation
negative regulation of cell growth
negative regulation of cell migration
BMP signaling pathway
positive regulation of BMP signaling pathway
activin receptor signaling pathway
wound healing, spreading of epidermal cells
intracellular signal transduction
endothelial cell activation
negative regulation of blood vessel endothelial cell migration
negative regulation of endothelial cell differentiation
positive regulation of endothelial cell differentiation
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
blood vessel morphogenesis
protein heterooligomerization
negative regulation of focal adhesion assembly
lymphatic endothelial cell differentiation
artery development
venous blood vessel development
endothelial tube morphogenesis
retina vasculature development in camera-type eye
cellular response to transforming growth factor beta stimulus
cellular response to BMP stimulus
negative regulation of DNA biosynthetic process

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor activity, type I
protein binding
ATP binding
kinase activity
activin receptor activity, type I
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
SMAD binding
metal ion binding
activin binding
transforming growth factor beta binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1500008449.mm.1	NM_001277255.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008449.mm.1	NM_001277257.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008449.mm.1	NM_001277258.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008449.mm.1	NM_001277259.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008449.mm.1	NM_009612.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008449.mm.1	TC1500001061.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1500008448.mm.1	NM_001277255.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008448.mm.1	NM_001277257.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008448.mm.1	NM_001277258.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008448.mm.1	NM_001277259.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008448.mm.1	NM_009612.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1500008448.mm.1	TC1500001061.mm.1	MTA TC