Mm00437568_g1

• Gene Symbol: Apoa1
• Gene Name: apolipoprotein A-I
• Gene Aliases: Alp-1, Apoa-1, Brp-14, Ltw-1, Lvtw-1, Sep-1, Sep-2, Sep2, apo-AI, apoA-I
• Chromosome Location: Chr.9: 46228630 - 46230469 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Apoa1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_009692.4	NP_033822.2	2 - 3	175		60
GenBank mRNA	AK076187.1	-	2 - 3	98		60
	AK149576.1	-	2 - 3	97		60
	AK161536.1	-	2 - 3	97		60
	BC012253.1	-	1 - 2	79	4195624	60
	BC019837.1	-	2 - 3	97	5123746	60
	BC091745.1	-	2 - 3	87	5126143	60
	L04151.1	-	1 - 2	88		60
	X64262.1	-	2 - 3	97		60

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0900000559.mm.1

Additional Information:

This assay is in the 5'UTR region of the BC091745.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Apoa1

Panther Classification:

Molecular Function -

apolipoprotein

Gene Ontology Categories:

Process(es)

regulation of protein phosphorylation
endothelial cell proliferation
negative regulation of cytokine secretion involved in immune response
lipid metabolic process
phospholipid metabolic process
phosphatidylcholine biosynthetic process
cholesterol biosynthetic process
transport
lipid transport
G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
protein localization
steroid metabolic process
cholesterol metabolic process
glucocorticoid metabolic process
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
negative regulation of very-low-density lipoprotein particle remodeling
phospholipid transport
protein oxidation
peptidyl-methionine modification
triglyceride catabolic process
lipid storage
regulation of intestinal cholesterol absorption
cholesterol transport
adrenal gland development
organ regeneration
axon regeneration
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
negative regulation of heterotypic cell-cell adhesion
very-low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
positive regulation of Rho protein signal transduction
lipoprotein metabolic process
lipoprotein biosynthetic process
cholesterol homeostasis
blood vessel endothelial cell migration
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
phosphatidylcholine metabolic process
negative regulation of interleukin-1 beta secretion
negative regulation of inflammatory response
protein stabilization
negative chemotaxis
positive regulation of lipoprotein lipase activity
vitamin transport
positive regulation of hydrolase activity
negative regulation of hydrolase activity
positive regulation of transferase activity
positive regulation of stress fiber assembly
phospholipid homeostasis
negative regulation of lipase activity
negative regulation of cell adhesion molecule production
negative regulation of response to cytokine stimulus
triglyceride homeostasis
cholesterol import
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

beta-amyloid binding
lipid transporter activity
protein binding
phospholipid binding
phospholipid transporter activity
high-density lipoprotein particle binding
lipid binding
cholesterol binding
cholesterol transporter activity
enzyme binding
phosphatidylcholine binding
apolipoprotein receptor binding
apolipoprotein A-I receptor binding
identical protein binding
chemorepellent activity
lipase inhibitor activity
phosphatidylcholine-sterol O-acyltransferase activator activity
high-density lipoprotein particle receptor binding
lipoprotein particle binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0900003919.mm.1	NM_009692.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0900003919.mm.1	TC0900000559.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	830658	-	-