Mm00438045_m1

• Gene Symbol: Casp3
• Gene Name: caspase 3
• Gene Aliases: A830040C14Rik, AC-3, Apopain, CASP-3, CC3, CPP-32, CPP32, Caspase-3, Lice, SCA-1, Yama, mldy
• Chromosome Location: Chr.8: 46617291 - 46639698 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Casp3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_009810.3	NP_033940.1	1 - 2	200		74
GenBank mRNA	U49929.1	-	1 - 2	42		74

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0800000541.mm.1

Additional Information:

This assay is in the 5'UTR region of the NM_009810.3,U49929.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Protease, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Casp3

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

B cell homeostasis
proteolysis
apoptotic process
cellular response to DNA damage stimulus
heart development
sensory perception of sound
learning or memory
response to UV
response to wounding
response to glucose
protein processing
neuron differentiation
keratinocyte differentiation
erythrocyte differentiation
negative regulation of B cell proliferation
glial cell apoptotic process
intracellular signal transduction
response to hydrogen peroxide
T cell homeostasis
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of neuron apoptotic process
cell fate commitment
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of cell cycle
negative regulation of activated T cell proliferation
neurotrophin TRK receptor signaling pathway
neuron apoptotic process
cellular response to organic substance
execution phase of apoptosis

Function(s)

protease binding
aspartic-type endopeptidase activity
cysteine-type endopeptidase activity
cyclin-dependent protein serine/threonine kinase inhibitor activity
death receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
phospholipase A2 activator activity
hydrolase activity
protein complex binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in execution phase of apoptosis

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0800003835.mm.1	NM_001284409.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0800003835.mm.1	NM_009810.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0800003835.mm.1	TC0800000541.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	456269	-	-
ABI Mouse Genome Survey Microarray	561901	-	-