Mm00439615_g1

• Gene Symbol: Il10
• Gene Name: interleukin 10
• Gene Aliases: CSIF, Il-10
• Chromosome Location: Chr.1: 131019845 - 131024970 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Il10
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010548.2	NP_034678.1	2 - 3	294		96
GenBank mRNA	AK152344.1	-	2 - 3	295		96
	BC120612.1	-	2 - 3	269	40129535	96
	BC137844.1	-	2 - 3	269	8860863	96
	M37897.1	-	2 - 3	302		96

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0100001167.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Apoptosis, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Il10

Gene Ontology Categories:

Process(es)

negative regulation of cytokine production
response to molecule of bacterial origin
negative regulation of cytokine secretion involved in immune response
negative regulation of chronic inflammatory response to antigenic stimulus
positive regulation of B cell apoptotic process
inflammatory response
immune response
regulation of gene expression
negative regulation of myeloid dendritic cell activation
negative regulation of B cell proliferation
negative regulation of interferon-gamma production
negative regulation of interleukin-12 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
receptor biosynthetic process
negative regulation of tumor necrosis factor biosynthetic process
defense response to bacterium
defense response to protozoan
negative regulation of apoptotic process
negative regulation of growth of symbiont in host
negative regulation of nitric oxide biosynthetic process
positive regulation of MHC class II biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JAK-STAT cascade
positive regulation of cytokine secretion
negative regulation of inflammatory response
negative regulation of membrane protein ectodomain proteolysis
positive regulation of sequence-specific DNA binding transcription factor activity
response to glucocorticoid
regulation of sensory perception of pain
negative regulation of cytokine activity
branching involved in labyrinthine layer morphogenesis
cellular response to lipopolysaccharide

Function(s)

cytokine activity
interleukin-10 receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0100009383.mm.1	NM_010548.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100009383.mm.1	NM_010548.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0100009383.mm.1	TC0100001167.mm.1	MTA TC