Assay Details

Gene Symbol: Il10
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010548.2	NP_034678.1	3 - 4	445		85
GenBank mRNA	BC120612.1	-	3 - 4	420	40129535	85
	BC137844.1	-	3 - 4	420	8860863	85
	M37897.1	-	3 - 4	453		85

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0100001167.mm.1

Set Membership:

Ambion siRNA available

Amplicon length between 71 and 85

Apoptosis

Mammalian Gene Collection

Mus musculus

Mouse Chemokine Panel

Mouse Immune Response

Inventoried

Mouse_Immune_Response

Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Il10

Gene Ontology Categories:

Function(s) Process(es)

MicroArray Probes:

Affymetrix

Citations (35)

Systemic PPARgamma ligation inhibits allergic immune response in the skin.

Authors: Dahten A, Koch C, Ernst D, Schnoller C, Hartmann S, Worm M
Journal: J Invest Dermatol - Page No 2211 (Mon Sep 01 00:00:00 EDT 2008)
Volume (Year): 128 (2008)
Product Usage: -

Cytokines, signaling pathways, and effector molecules required for the control of Leishmania (Viannia) braziliensis in mice.

Authors: Rocha FJ, Schleicher U, Mattner J, Alber G, Bogdan C
Journal: Infect Immun - Page No 3823 (Wed Aug 01 00:00:00 EDT 2007)
Volume (Year): 75 (2007)
Product Usage: -

Early cytokine expression in mouse sciatic nerve after chronic constriction nerve injury depends on calpain.

Authors: Uceyler N, Tscharke A, Sommer C
Journal: Brain Behav Immun - Page No 553 (Sun Jul 01 00:00:00 EDT 2007)
Volume (Year): 21 (2007)
Product Usage: -

Nitric oxide synthase modulates CFA-induced thermal hyperalgesia through cytokine regulation in mice.

Authors: Chen Y, Boettger MK, Reif A, Schmitt A, Uceyler N, Sommer C
Journal: Mol Pain - Page No 13 (Fri Jan 01 00:00:00 EST 2010)
Volume (Year): 6 (2010)
Product Usage: -

Deletion of bradykinin B1 receptor reduces renal fibrosis.

Authors: Wang PH, Cenedeze MA, Campanholle G, Malheiros DM, Torres HA, Pesquero JB, Pacheco-Silva A, Camara NO
Journal: Int Immunopharmacol - Page No 653 (Mon Jun 01 00:00:00 EDT 2009)
Volume (Year): 9 (2009)
Product Usage: -

Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators.

Authors: Osada Y, Shimizu S, Kumagai T, Yamada S, Kanazawa T
Journal: Int J Parasitol - Page No 457 (Sun Mar 01 00:00:00 EST 2009)
Volume (Year): 39 (2009)
Product Usage: -

The proteasome inhibitor bortezomib aggravates renal ischemia-reperfusion injury.

Authors: Huber JM, Tagwerker A, Heininger D, Mayer G, Rosenkranz AR, Eller K
Journal: Am J Physiol Renal Physiol - Page No F451 (Sat Aug 01 00:00:00 EDT 2009)
Volume (Year): 297 (2009)
Product Usage: -

Increased expression of cathepsins and obesity-induced proinflammatory cytokines in lacrimal glands of male NOD mouse.

Authors: Li X, Wu K, Edman M, Schenke-Layland K, MacVeigh-Aloni M, Janga SR, Schulz B, Hamm-Alvarez SF
Journal: Invest Ophthalmol Vis Sci - Page No 5019 (Fri Oct 01 00:00:00 EDT 2010)
Volume (Year): 51 (2010)
Product Usage: -

Bacterial lipoproteins can disseminate from the periphery to inflame the brain.

Authors: Londono D, Cadavid D
Journal: Am J Pathol - Page No 2848 (Tue Jun 01 00:00:00 EDT 2010)
Volume (Year): 176 (2010)
Product Usage: -

Psychological stress increases expression of IL-10 and its homolog IL-19 via beta-adrenoceptor activation: reversal by the anxiolytic chlordiazepoxide.

Authors: Curtin NM, Mills KH, Connor TJ
Journal: Brain Behav Immun - Page No 371 (Sun Mar 01 00:00:00 EST 2009)
Volume (Year): 23 (2009)
Product Usage: -

Mutant alpha-synuclein overexpression mediates early proinflammatory activity.

Authors: Su X, Federoff HJ, Maguire-Zeiss KA
Journal: Neurotox Res - Page No 238 (Thu Oct 01 00:00:00 EDT 2009)
Volume (Year): 16 (2009)
Product Usage: -

Differential effects of rapamycin in anti-GBM glomerulonephritis.

Authors: Hochegger K, Jansky GL, Soleiman A, Wolf AM, Tagwerker A, Seger C, Griesmacher A, Mayer G, Rosenkranz AR
Journal: J Am Soc Nephrol - Page No 1520 (Fri Aug 01 00:00:00 EDT 2008)
Volume (Year): 19 (2008)
Product Usage: -

Effect of HeNe laser irradiation on extracellular matrix deposition and expression of cytokines and chemokines in paracoccidioidomycotic lesions.

Authors: Nagib PR, Gameiro J, da Costa TA, Di Gangi R, Ribeiro Jda S, Paulino LC, Verinaud L
Journal: Photochem Photobiol - Page No 920 (Thu Jul 01 00:00:00 EDT 2010)
Volume (Year): 86 (2010)
Product Usage: -

Deficiency of the negative immune regulator B7-H1 enhances inflammation and neuropathic pain after chronic constriction injury of mouse sciatic nerve.

Authors: Uceyler N, Gobel K, Meuth SG, Ortler S, Stoll G, Sommer C, Wiendl H, Kleinschnitz C
Journal: Exp Neurol - Page No 153 (Mon Mar 01 00:00:00 EST 2010)
Volume (Year): 222 (2010)
Product Usage: -

Kupffer cell-dependent TNF-alpha signaling mediates injury in the arterialized small-for-size liver transplantation in the mouse.

Authors: Tian Y, Jochum W, Georgiev P, Moritz W, Graf R, Clavien PA
Journal: Proc Natl Acad Sci U S A - Page No 4598 (Tue Mar 21 00:00:00 EST 2006)
Volume (Year): 103 (2006)
Product Usage: -

Atorvastatin attenuates murine anti-glomerular basement membrane glomerulonephritis.

Authors: Eller P, Eller K, Wolf AM, Reinstadler SJ, Tagwerker A, Patsch JR, Mayer G, Rosenkranz AR
Journal: Kidney Int - Page No 428 (Mon Mar 01 00:00:00 EST 2010)
Volume (Year): 77 (2010)
Product Usage: -

Induction of Foxp3+ regulatory T cells with histone deacetylase inhibitors.

Authors: Lucas JL, Mirshahpanah P, Haas-Stapleton E, Asadullah K, Zollner TM, Numerof RP
Journal: Cell Immunol - Page No 97 (Thu Jan 01 00:00:00 EST 2009)
Volume (Year): 257 (2009)
Product Usage: -

Orally administered lactoperoxidase ameliorates dextran sulfate sodium-induced colitis in mice by up-regulating colonic interleukin-10 and maintaining peripheral regulatory T cells.

Authors: Shin K, Horigome A, Yamauchi K, Yaeshima T, Iwatsuki K
Journal: Int Immunopharmacol - Page No 1387 (Sun Nov 01 00:00:00 EDT 2009)
Volume (Year): 9 (2009)
Product Usage: -

Modulation of acute diarrheal illness by persistent bacterial infection.

Authors: McBee ME, Zheng PZ, Rogers AB, Fox JG, Schauer DB
Journal: Infect Immun - Page No 4851 (Sat Nov 01 00:00:00 EDT 2008)
Volume (Year): 76 (2008)
Product Usage: -

Both TLR2 and TLR4 are required for the effective immune response in Staphylococcus aureus-induced experimental murine brain abscess.

Authors: Stenzel W, Soltek S, Sanchez-Ruiz M, Akira S, Miletic H, Schluter D, Deckert M
Journal: Am J Pathol - Page No 132 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year): 172 (2008)
Product Usage: -

Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo.

Authors: Gitlin L, Benoit L, Song C, Cella M, Gilfillan S, Holtzman MJ, Colonna M
Journal: Plos Pathog - Page No e1000734 (Fri Jan 01 00:00:00 EST 2010)
Volume (Year): 6 (2010)
Product Usage: -

Topical delivery of silver nanoparticles promotes wound healing.

Authors: Tian J, Wong KK, Ho CM, Lok CN, Yu WY, Che CM, Chiu JF, Tam PK
Journal: Chemmedchem - Page No 129 (Mon Jan 01 00:00:00 EST 2007)
Volume (Year): 2 (2007)
Product Usage: -

Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice.

Authors: Kelly J, Ali Khan A, Yin J, Ferguson TA, Apte RS
Journal: J Clin Invest - Page No 3421 (Thu Nov 01 00:00:00 EDT 2007)
Volume (Year): 117 (2007)
Product Usage: -

Tumor necrosis factor-alpha: alternative role as an inhibitor of osteoclast formation in vitro.

Authors: Balga R, Wetterwald A, Portenier J, Dolder S, Mueller C, Hofstetter W
Journal: Bone - Page No 325 (Tue Aug 01 00:00:00 EDT 2006)
Volume (Year): 39 (2006)
Product Usage: -

Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis.

Authors: Centonze D, Muzio L, Rossi S, Cavasinni F, De Chiara V, Bergami A, Musella A, D'Amelio M, Cavallucci V, Martorana A, Bergamaschi A, Cencioni MT, Diamantini A, Butti E, Comi G, Bernardi G, Cecconi F, Battistini L, Furlan R, Martino G
Journal: J Neurosci - Page No 3442 (Wed Mar 18 00:00:00 EDT 2009)
Volume (Year): 29 (2009)
Product Usage: -

CD4(+)CD25 (+) Regulatory T Cells Suppress Th17-Responses in an Experimental Colitis Model.

Authors: Ogino H, Nakamura K, Ihara E, Akiho H, Takayanagi R
Journal: Dig Dis Sci - Page No (Thu Jun 03 00:00:00 EDT 2010)
Volume (Year): (2010)
Product Usage: -

Regulation of the inflammatory response to Staphylococcus aureus-induced brain abscess by interleukin-10.

Authors: Stenzel W, Dahm J, Sanchez-Ruiz M, Miletic H, Hermann M, Courts C, Schwindt H, Utermohlen O, Schluter D, Deckert M
Journal: J Neuropathol Exp Neurol - Page No 1046 (Thu Dec 01 00:00:00 EST 2005)
Volume (Year): 64 (2005)
Product Usage: -

Modulation of dendritic cell function by naive and regulatory CD4+ T cells.

Authors: Veldhoen M, Moncrieffe H, Hocking RJ, Atkins CJ, Stockinger B
Journal: J Immunol - Page No 6202 (Mon May 15 00:00:00 EDT 2006)
Volume (Year): 176 (2006)
Product Usage: -

TLR4-mediated induction of TLR2 signaling is critical in the pathogenesis and resolution of otitis media.

Authors: Leichtle A, Hernandez M, Pak K, Yamasaki K, Cheng CF, Webster NJ, Ryan AF, Wasserman SI
Journal: Innate Immun - Page No 205 (Sat Aug 01 00:00:00 EDT 2009)
Volume (Year): 15 (2009)
Product Usage: -

CD8 T cells producing IL-17 and IFN-gamma initiate the innate immune response required for responses to antigen skin challenge.

Authors: Kish DD, Li X, Fairchild RL
Journal: J Immunol - Page No 5949 (Fri May 15 00:00:00 EDT 2009)
Volume (Year): 182 (2009)
Product Usage: -

Beneficial effect of brewers' yeast extract on daily activity in a murine model of chronic fatigue syndrome.

Authors: Takahashi T, Yu F, Zhu SJ, Moriya J, Sumino H, Morimoto S, Yamaguchi N, Kanda T
Journal: Evid Based Complement Alternat Med - Page No 109 (Wed Mar 01 00:00:00 EST 2006)
Volume (Year): 3 (2006)
Product Usage: -

Administration of neural precursor cells ameliorates renal ischemia-reperfusion injury.

Authors: Wang PH, Schwindt TT, Barnabe GF, Motta FL, Semedo P, Beraldo FC, Mazzali M, Dos Reis MA, Teixeira Vde P, Pacheco-Silva A, Mello LE, Camara NO
Journal: Nephron Exp Nephrol - Page No e20 (Thu Jan 01 00:00:00 EST 2009)
Volume (Year): 112 (2009)
Product Usage: -

Topical omega-3 and omega-6 fatty acids for treatment of dry eye.

Authors: Rashid S, Jin Y, Ecoiffier T, Barabino S, Schaumberg DA, Dana MR
Journal: Arch Ophthalmol - Page No 219 (Fri Feb 01 00:00:00 EST 2008)
Volume (Year): 126 (2008)
Product Usage: -

IL-9 Production by Regulatory T Cells Recruits Mast Cells That Are Essential for Regulatory T Cell-Induced Immune Suppression.

Authors: Eller K, Wolf D, Huber JM, Metz M, Mayer G, McKenzie AN, Maurer M, Rosenkranz AR, Wolf AM
Journal: J Immunol - Page No (Mon Nov 29 00:00:00 EST 2010)
Volume (Year): (2010)
Product Usage: -

Impact of systemic histamine deficiency on the crosstalk between mammary adenocarcinoma and T cells.

Authors: Hegyesi H, Colombo L, Pallinger E, Toth S, Boer K, Molnar V, Falus A
Journal: J Pharmacol Sci - Page No 66 (Sat Sep 01 00:00:00 EDT 2007)
Volume (Year): 105 (2007)
Product Usage: -

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Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0100009384.mm.1	NM_010548.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100009384.mm.1	NM_010548.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0100009384.mm.1	TC0100001167.mm.1	MTA TC

System Message

Genomic Map