Mm00439648_m1

• Gene Symbol: Il6ra
• Gene Name: interleukin 6 receptor, alpha
• Gene Aliases: CD126, IL-6R, Il6r
• Chromosome Location: Chr.3: 89868829 - 89913492 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Il6ra
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010559.2	NP_034689.2	1 - 2	214		104
GenBank mRNA	AK046337.1	-	1 - 2	213		104
	AK082270.1	-	1 - 2	214		104
	AK141197.1	-	1 - 2	249		104
	BC019388.1	-	1 - 2	208		104
	X51975.1	-	1 - 2	105		104
	X51976.1	-		94		104
	X53802.1	-	1 - 2	214		104

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0300002357.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, 1700, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Il6ra

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

positive regulation of cell proliferation
positive regulation of activation of Janus kinase activity
cell growth
cytokine-mediated signaling pathway
endocrine pancreas development
positive regulation of chemokine production
positive regulation of interleukin-6 production
negative regulation of collagen biosynthetic process
response to cytokine
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of MAPK cascade
positive regulation of JAK-STAT cascade
positive regulation of smooth muscle cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
interleukin-6-mediated signaling pathway
ciliary neurotrophic factor-mediated signaling pathway

Function(s)

cytokine receptor activity
ciliary neurotrophic factor receptor activity
interleukin-6 receptor activity
interleukin-6 receptor binding
enzyme binding
interleukin-6 binding
protein homodimerization activity
ciliary neurotrophic factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	526964	-	-
ABI Mouse Genome Survey Microarray	694120	-	-