Mm00439656_m1

• Gene Symbol: Il6st
• Gene Name: interleukin 6 signal transducer
• Gene Aliases: 5133400A03Rik, AA389424, BB405851, CD130, D13Ertd699e, gp130
• Chromosome Location: Chr.13: 112464070 - 112506860 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Il6st
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010560.3	NP_034690.3	2 - 3	275		97
GenBank mRNA	AK170020.1	-	3 - 4	437		97
	BC020454.1	-	2 - 3	229		97
	BC058679.1	-	2 - 3	236	6834623	97
	M83336.1	-	1 - 2	80		97
	X62646.1	-	1 - 2	80		97

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1300001265.mm.1

Additional Information:

This assay is in the 5'UTR region of the AK170020.1,BC058679.1,M83336.1,NM_010560.3,X62646.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Il6st

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

glycogen metabolic process
triglyceride mobilization
signal transduction
positive regulation of cell proliferation
regulation of Notch signaling pathway
positive regulation of smooth muscle cell migration
cytokine-mediated signaling pathway
response to cytokine
oncostatin-M-mediated signaling pathway
positive regulation of T cell proliferation
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of osteoblast differentiation
positive regulation of astrocyte differentiation
leukemia inhibitory factor signaling pathway
negative regulation of cytosolic calcium ion concentration
interleukin-6-mediated signaling pathway
negative regulation of interleukin-6-mediated signaling pathway
interleukin-27-mediated signaling pathway
ciliary neurotrophic factor-mediated signaling pathway

Function(s)

cytokine receptor activity
ciliary neurotrophic factor receptor activity
interleukin-6 receptor activity
interleukin-11 receptor activity
leukemia inhibitory factor receptor activity
oncostatin-M receptor activity
ciliary neurotrophic factor receptor binding
interleukin-6 receptor binding
protein binding
growth factor binding
interleukin-11 binding
interleukin-6 binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1300007984.mm.1	NM_010560.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1300007984.mm.1	NM_010560.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1300007984.mm.1	TC1300001265.mm.1	MTA TC