Mm00439868_m1

• Gene Symbol: Itk
• Gene Name: IL2 inducible T cell kinase
• Gene Aliases: Emt, Tcsk, Tsk
• Chromosome Location: Chr.11: 46325148 - 46389515 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Itk
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001281965.1	NP_001268894.1	12 - 13	1354		81
	NM_001281966.1	NP_001268895.1	12 - 13	1345		81
	NM_001281968.1	NP_001268897.1	12 - 13	1333		81
	NM_010583.3	NP_034713.2	12 - 13	1336		81
GenBank mRNA	AK037554.1	-		416		81
	AK083380.1	-	12 - 13	1308		81
	AK153613.1	-	12 - 13	1292		81
	BC128374.1	-	12 - 13	1262	40111687	81
	BC128375.1	-	12 - 13	1259	40111688	81
	D14042.1	-	12 - 13	1276		81
	L00619.1	-	12 - 13	1341		81
	L05631.1	-	12 - 13	1302		81

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100002602.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Itk

Gene Ontology Categories:

Process(es)

cytokine production
NK T cell differentiation
adaptive immune response
immune system process
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
activation of phospholipase C activity
phosphorylation
peptidyl-tyrosine phosphorylation
interferon-gamma production
interleukin-4 production
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
T cell receptor signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding