Mm00440649_g1

• Gene Symbol: Furin
• Gene Name: furin (paired basic amino acid cleaving enzyme)
• Gene Aliases: 9130404I01Rik, Fur, PACE, Pcsk3, SPC1
• Chromosome Location: Chr.7: 80389194 - 80405445 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Furin
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001081454.1	NP_001074923.1	11 - 12	1535		79
	NM_011046.2	NP_035176.1	11 - 12	1655		79
GenBank mRNA	BC048234.1	-	10 - 11	1362	6492009	79
	L26489.1	-	11 - 12	1655		79
	X54056.1	-	10 - 11	1358		79

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0700003594.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protease, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Furin

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

signal peptide processing
proteolysis
cell proliferation
regulation of signal transduction
negative regulation of endopeptidase activity
protein processing
peptide hormone processing
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of low-density lipoprotein particle receptor catabolic process
nerve growth factor production
negative regulation of transforming growth factor beta1 production
secretion by cell
regulation of protein catabolic process
peptide biosynthetic process
regulation of low-density lipoprotein particle receptor biosynthetic process
regulation of endopeptidase activity

Function(s)

protease binding
endopeptidase activity
serine-type endopeptidase activity
serine-type endopeptidase inhibitor activity
protein binding
peptidase activity
serine-type peptidase activity
hydrolase activity
peptide binding
metal ion binding
nerve growth factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0700030463.mm.1	NM_001081454.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0700030463.mm.1	NM_011046.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0700030463.mm.1	TC0700003594.mm.1	MTA TC