Mm00440685_g1

• Gene Symbol: Pdgfra
• Gene Name: platelet derived growth factor receptor, alpha polypeptide
• Gene Aliases: AI115593, CD140a, Pdgfr-2
• Chromosome Location: Chr.5: 75151401 - 75198211 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pdgfra
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001083316.1	NP_001076785.1	6 - 7	1128		84
	NM_011058.2	NP_035188.2	6 - 7	1111		84
GenBank mRNA	AK035501.1	-	6 - 7	1068		84
	AK081664.1	-	6 - 7	1110		84
	AK136490.1	-	6 - 7	1097		84
	AK139094.1	-	5 - 6	1343		84
	AK145097.1	-	6 - 7	1711		84
	AK147267.1	-	6 - 7	1060		84
	AK163952.1	-	6 - 7	1175		84
	BC020405.1	-	6 - 7	1042		84
	BC037467.1	-	6 - 7	1050		84
	BC053036.1	-	6 - 7	1128	5704645	84
	M84607.1	-	6 - 7	1121		84

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500000709.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pdgfra

Gene Ontology Categories:

Process(es)

luteinization
in utero embryonic development
hematopoietic progenitor cell differentiation
protein phosphorylation
chemotaxis
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cytosolic calcium ion concentration
multicellular organism development
estrogen metabolic process
positive regulation of cell proliferation
female gonad development
anatomical structure morphogenesis
organ morphogenesis
negative regulation of platelet activation
positive regulation of phospholipase C activity
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
signal transduction involved in regulation of gene expression
extracellular matrix organization
lung development
adrenal gland development
positive regulation of cell migration
male genitalia development
Leydig cell differentiation
cellular response to reactive oxygen species
platelet-derived growth factor receptor-alpha signaling pathway
cellular response to platelet-derived growth factor stimulus
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
wound healing
odontogenesis of dentin-containing tooth
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of DNA replication
protein autophosphorylation
platelet-derived growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of fibroblast proliferation
embryonic digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
regulation of chemotaxis
cardiac myofibril assembly
palate development
face morphogenesis
cell chemotaxis
retina vasculature development in camera-type eye
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
cellular response to amino acid stimulus
metanephric glomerular capillary formation
regulation of mesenchymal stem cell differentiation

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
platelet-derived growth factor alpha-receptor activity
vascular endothelial growth factor-activated receptor activity
platelet-derived growth factor receptor binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein complex binding
vascular endothelial growth factor binding
protein homodimerization activity
phosphatidylinositol 3-kinase binding
platelet-derived growth factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500006256.mm.1	TC0500000709.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500006256.mm.1	NM_001083316.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0500006256.mm.1	NM_011058.3	Refseq