Mm00440702_m1

• Gene Symbol: Pdpk1
• Gene Name: 3-phosphoinositide dependent protein kinase 1
• Gene Aliases: Pdk1
• Chromosome Location: Chr.17: 24073680 - 24150922 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pdpk1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001080773.2	NP_001074242.1	1 - 2	155		79
	NM_011062.4	NP_035192.2	1 - 2	155		79
GenBank mRNA	AF079535.1	-	1 - 2	112		79
	AF086625.1	-	1 - 2	121		79
	AF126294.1	-	1 - 2	96		79
	AK143283.1	-	1 - 2	118		79
	AK147149.1	-	1 - 2	147		79
	AK147835.1	-	1 - 2	130		79
	AK149162.1	-	1 - 2	88		79
	AK149289.1	-	1 - 2	113		79
	AK162677.1	-	1 - 2	115		79
	AK165564.1	-	1 - 2	92		79
	BC146001.1	-	1 - 2	92	40131304	79
	BC146003.1	-	1 - 2	92	40131306	79
	BY257456.1	-	1 - 2	156		79

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700001615.mm.1

Additional Information:

This assay is in the 5'UTR region of the AF079535.1,AF086625.1,AF126294.1,AK147149.1,AK147835.1,AK149289.1,AK162677.1,BC146001.1,BC146003.1,NM_001080773.2,NM_011062.4 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protein Kinase, Mammalian Gene Collection, Mus musculus, 1700, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pdpk1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
phosphorylation
cell migration
peptidyl-threonine phosphorylation
calcium-mediated signaling
negative regulation of transforming growth factor beta receptor signaling pathway
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
focal adhesion assembly
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
protein binding
ATP binding
phospholipase activator activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
phospholipase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700014192.mm.1	NM_001080773.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014192.mm.1	NM_001286662.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014192.mm.1	NM_011062.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014192.mm.1	NM_011062.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014192.mm.1	TC1700001615.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700014167.mm.1	NM_001080773.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014167.mm.1	NM_001286662.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014167.mm.1	NM_011062.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014167.mm.1	NM_011062.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014167.mm.1	TC1700001615.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700014196.mm.1	NM_001080773.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014196.mm.1	NM_011062.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014196.mm.1	NM_011062.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014196.mm.1	TC1700001615.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	906897	-	-