Mm00440706_m1

• Gene Symbol: Pdpk1
• Gene Name: 3-phosphoinositide dependent protein kinase 1
• Gene Aliases: Pdk1
• Chromosome Location: Chr.17: 24073680 - 24150922 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pdpk1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001080773.2	NP_001074242.1	5 - 6	750		106
	NM_001286662.1	NP_001273591.1	5 - 6	668		106
	NM_011062.4	NP_035192.2	5 - 6	750		106
GenBank mRNA	AF079535.1	-	5 - 6	707		106
	AF086625.1	-	5 - 6	716		106
	AF126294.1	-	5 - 6	691		106
	AK147149.1	-	5 - 6	742		106
	AK147835.1	-	5 - 6	725		106
	AK149162.1	-	5 - 6	684		107
	AK149289.1	-	5 - 6	708		106
	AK162677.1	-	5 - 6	710		106
	AY062008.1	-	5 - 6	646		106
	BC146001.1	-	5 - 6	687	40131304	106
	BC146003.1	-	5 - 6	687	40131306	106

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700001615.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pdpk1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
phosphorylation
cell migration
peptidyl-threonine phosphorylation
calcium-mediated signaling
negative regulation of transforming growth factor beta receptor signaling pathway
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
focal adhesion assembly
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
protein binding
ATP binding
phospholipase activator activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
phospholipase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700014183.mm.1	NM_001080773.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014183.mm.1	NM_001286662.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014183.mm.1	NM_011062.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014183.mm.1	NM_011062.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014183.mm.1	TC1700001615.mm.1	MTA TC