Mm00440855_m1

• Gene Symbol: Prkca
• Gene Name: protein kinase C, alpha
• Gene Aliases: AI875142, Pkca
• Chromosome Location: Chr.11: 107933387 - 108343888 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Prkca
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011101.3	NP_035231.2	13 - 14	1743		72
GenBank mRNA	AK147084.1	-	13 - 14	1744		72
	AK163950.1	-	3 - 4	431		72
	BC096493.1	-	13 - 14	1537	30742571	72
	M25811.1	-	13 - 14	1777		72
	X52684.1	-	14 - 15	1684		72
	X52685.1	-	14 - 15	1684		72

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100003966.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Protein Kinase, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Prkca

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

inactivation of MAPK activity
response to reactive oxygen species
angiogenesis
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
regulation of the force of heart contraction
chondrocyte differentiation
desmosome assembly
protein phosphorylation
negative regulation of protein kinase activity
cellular calcium ion homeostasis
apoptotic process
regulation of muscle contraction
cell adhesion
learning or memory
negative regulation of cell proliferation
positive regulation of endothelial cell migration
positive regulation of cardiac muscle hypertrophy
phosphorylation
negative regulation of translation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
central nervous system neuron axonogenesis
positive regulation of cell migration
neutrophil chemotaxis
positive regulation of lipopolysaccharide-mediated signaling pathway
response to estradiol
negative regulation of glial cell apoptotic process
histone H3-T6 phosphorylation
intracellular signal transduction
peptidyl-serine autophosphorylation
positive regulation of blood vessel endothelial cell migration
response to ethanol
positive regulation of macrophage differentiation
positive regulation of angiogenesis
positive regulation of cell adhesion
negative regulation of heart contraction
positive regulation of exocytosis
positive regulation of mitotic cell cycle
negative regulation of glucose import
negative regulation of insulin receptor signaling pathway
protein autophosphorylation
regulation of receptor-mediated endocytosis
positive regulation of smooth muscle cell proliferation
positive regulation of inflammatory response
regulation of peptidyl-tyrosine phosphorylation
induction of positive chemotaxis
positive regulation of synapse assembly
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
cellular response to carbohydrate stimulus
regulation of platelet aggregation
intrinsic apoptotic signaling pathway
positive regulation of dense core granule biogenesis

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
calcium-dependent protein kinase C activity
protein binding
ATP binding
zinc ion binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
enzyme binding
histone kinase activity (H3-T6 specific)
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100037222.mm.1	NM_011101.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100037222.mm.1	NM_011101.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100037222.mm.1	TC1100003966.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100037223.mm.1	NM_011101.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100037223.mm.1	NM_011101.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100037223.mm.1	TC1100003966.mm.1	MTA TC