Mm00440940_m1 Best Coverage

• Gene Symbol: Pparg
• Gene Name: peroxisome proliferator activated receptor gamma
• Gene Aliases: Nr1c3, PPAR-gamma, PPAR-gamma2, PPARgamma, PPARgamma2
• Chromosome Location: Chr.6: 115360879 - 115490404 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pparg
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011146.3	NP_035276.2	1 - 2	124		63
GenBank mRNA	AY208183.1	-	1 - 2	124		63
	AY208184.1	-	1 - 2	124		63
	AY243585.1	-	1 - 2	124		63
	BC021798.1	-	1 - 2	124	4191539	63
	CT010340.1	-	1 - 2	79		63
	EF062476.1	-	1 - 2	115		63
	U09138.1	-	1 - 2	118		63

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0600001279.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Nuclear Receptor, Mammalian Gene Collection, Recommended Assay, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pparg

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
negative regulation of cytokine production
placenta development
response to dietary excess
diet induced thermogenesis
negative regulation of acute inflammatory response
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
signal transduction
regulation of blood pressure
negative regulation of cell proliferation
response to light stimulus
regulation of gene expression
negative regulation of macrophage derived foam cell differentiation
negative regulation of receptor biosynthetic process
negative regulation of cholesterol storage
negative regulation of sequestering of triglyceride
long-chain fatty acid transport
regulation of lipid metabolic process
fatty acid oxidation
monocyte differentiation
negative regulation of cell growth
intracellular receptor signaling pathway
epithelial cell differentiation
response to food
response to retinoic acid
cellular response to insulin stimulus
negative regulation of collagen biosynthetic process
response to lipid
peroxisome proliferator activated receptor signaling pathway
glucose homeostasis
regulation of circadian rhythm
lipoprotein transport
positive regulation of apoptotic process
steroid hormone mediated signaling pathway
cell fate commitment
fat cell differentiation
regulation of fat cell differentiation
positive regulation of fat cell differentiation
low-density lipoprotein particle receptor biosynthetic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fatty acid oxidation
cell maturation
rhythmic process
negative regulation of smooth muscle cell proliferation
positive regulation of oligodendrocyte differentiation
white fat cell differentiation
brown fat cell differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of telomerase activity
response to low-density lipoprotein particle
positive regulation of phagocytosis, engulfment
negative regulation of interferon-gamma-mediated signaling pathway
regulation of transcription involved in cell fate commitment
cellular response to lithium ion
cellular response to organic cyclic compound
negative regulation of peptide hormone secretion
negative regulation of cellular response to insulin stimulus
negative regulation of pancreatic stellate cell proliferation

Function(s)

RNA polymerase II regulatory region DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
transcription factor binding
drug binding
zinc ion binding
enzyme binding
protein phosphatase binding
estrogen receptor binding
ligand-dependent nuclear receptor transcription coactivator activity
activating transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
retinoid X receptor binding
arachidonic acid binding
WW domain binding
alpha-actinin binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0600010093.mm.1	TC0600001279.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0600010093.mm.1	NM_011146.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0600010093.mm.1	NM_011146.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0600010094.mm.1	TC0600001279.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0600010094.mm.1	NM_001127330.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0600010094.mm.1	NM_011146.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0600010094.mm.1	NM_011146.3	Refseq

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	551619	-	-