Mm00440970_g1

• Gene Symbol: Eif2ak2
• Gene Name: eukaryotic translation initiation factor 2-alpha kinase 2
• Gene Aliases: 2310047A08Rik, 4732414G15Rik, AI467567, AI747578, Pkr, Prkr, Tik
• Chromosome Location: Chr.17: 78852550 - 78882572 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Eif2ak2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011163.4	NP_035293.1	5 - 6	690		71
GenBank mRNA	AK028602.1	-	5 - 6	690		71
	BC016422.1	-	5 - 6	653	3964935	71
	M65029.1	-	5 - 6	642		71
	M93567.1	-	5 - 6	632		71

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700002558.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Protein Kinase, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Eif2ak2

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
positive regulation of cytokine production
immune system process
transcription, DNA-templated
regulation of transcription, DNA-templated
translation
protein phosphorylation
response to virus
response to toxic substance
phosphorylation
negative regulation of translation
endoplasmic reticulum unfolded protein response
response to lipopolysaccharide
positive regulation of chemokine production
positive regulation of stress-activated MAPK cascade
response to vitamin E
negative regulation of osteoblast proliferation
response to interferon-alpha
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of viral genome replication
innate immune response
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
defense response to virus
regulation of NLRP3 inflammasome complex assembly
positive regulation of NIK/NF-kappaB signaling
regulation of hematopoietic progenitor cell differentiation
regulation of hematopoietic stem cell proliferation
regulation of hematopoietic stem cell differentiation

Function(s)

nucleotide binding
RNA binding
double-stranded RNA binding
protein kinase activity
protein serine/threonine kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
poly(A) RNA binding