Mm00441523_mH

• Gene Symbol: Slc8a1
• Gene Name: solute carrier family 8 (sodium/calcium exchanger), member 1
• Gene Aliases: AI852629, AV344025, D930008O12Rik, Ncx1
• Chromosome Location: Chr.17: 81373105 - 81738387 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Slc8a1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001112798.2	NP_001106269.1	6 - 7	2235		73
	NM_001286684.1	NP_001273613.1	8 - 9	2271		73
	NM_011406.3	NP_035536.2	8 - 9	2271		73
	NR_104580.1		6 - 7	2270		73
GenBank mRNA	AF004666.1	-	8 - 9	2266		73
	AK048160.1	-		1733		73
	BC079673.1	-	5 - 6	2126	30532156	73
	DQ388998.1	-	5 - 6	2160		73

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700002597.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Transporter, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Slc8a1

Panther Classification:

Molecular Function -

secondary carrier transporter

Gene Ontology Categories:

Process(es)

response to hypoxia
embryonic placenta development
regulation of the force of heart contraction
regulation of heart rate
regulation of sodium ion transport
heart morphogenesis
transport
ion transport
sodium ion transport
calcium ion transport
cellular calcium ion homeostasis
cellular sodium ion homeostasis
cell communication
positive regulation of cytosolic calcium ion concentration
post-embryonic development
positive regulation of fibroblast migration
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
vascular smooth muscle contraction
positive regulation of bone mineralization
response to ATP
cellular response to reactive oxygen species
embryonic heart tube development
sodium ion transmembrane transport
response to muscle stretch
relaxation of smooth muscle
muscle fiber development
negative regulation of cytosolic calcium ion concentration
regulation of calcium ion transport
cardiac muscle cell development
calcium ion homeostasis
transmembrane transport
cardiac muscle contraction
calcium ion transport into cytosol
calcium ion import
calcium ion transmembrane transport
cellular response to caffeine
cellular response to cAMP
sodium ion export
regulation of cardiac muscle cell membrane potential
cell communication by electrical coupling involved in cardiac conduction
sodium ion import
positive regulation of the force of heart contraction
calcium ion export

Function(s)

calcium:sodium antiporter activity
protein binding
calmodulin binding
cytoskeletal protein binding
antiporter activity
ankyrin binding
ion channel binding
metal ion binding
calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential