Mm00441665_m1

• Gene Symbol: Tal1
• Gene Name: T cell acute lymphocytic leukemia 1
• Gene Aliases: SCL/tal-1, Scl, bHLHa17, tal-1
• Chromosome Location: Chr.4: 115056426 - 115071755 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Tal1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001287388.1	NP_001274317.1	3 - 4	658		97
	NM_011527.3	NP_035657.1	3 - 4	641		97
GenBank mRNA	AK144164.1	-	2 - 3	612		97
	AK157852.1	-	3 - 4	659		97
	BC063060.1	-	3 - 4	641	6826611	97
	M59764.1	-	2 - 3	589		97

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0400001216.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Tal1

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
locomotory behavior
spinal cord association neuron differentiation
hemopoiesis
myeloid cell differentiation
cell differentiation
neuron differentiation
erythrocyte differentiation
megakaryocyte differentiation
platelet formation
positive regulation of protein complex assembly
embryonic hemopoiesis
megakaryocyte development
regulation of cell proliferation
erythrocyte maturation
cell fate commitment
regulation of myeloid cell differentiation
positive regulation of erythrocyte differentiation
positive regulation of chromatin assembly or disassembly
positive regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
generation of neurons
positive regulation of cell division
astrocyte fate commitment
definitive hemopoiesis
hemangioblast cell differentiation
hematopoietic stem cell differentiation
regulation of mast cell differentiation
regulation of stem cell population maintenance

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
enzyme binding
histone deacetylase binding
transcription regulatory region DNA binding
protein heterodimerization activity
protein dimerization activity
E-box binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0400008859.mm.1	NM_001287388.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400008859.mm.1	NM_011527.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0400008859.mm.1	TC0400001216.mm.1	MTA TC