Mm00441822_m1

• Gene Symbol: Timp2
• Gene Name: tissue inhibitor of metalloproteinase 2
• Gene Aliases: D11Bwg1104e, Timp-2
• Chromosome Location: Chr.11: 118301061 - 118355411 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Timp2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011594.3	NP_035724.2	1 - 2	445		61
GenBank mRNA	AK081522.1	-	1 - 2	541		61
	AK144236.1	-	1 - 2	360		61
	BC049126.1	-	1 - 2	342	6821553	61
	M82858.1	-	1 - 2	340		61
	M93954.1	-	1 - 2	132		61
	X62622.1	-	1 - 2	350		61

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100004157.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, 1700, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Timp2

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

negative regulation of cell proliferation
response to hormone
negative regulation of peptidase activity
negative regulation of endopeptidase activity
regulation of cAMP metabolic process
regulation of Rap protein signal transduction
response to cytokine
positive regulation of catalytic activity
negative regulation of catalytic activity
regulation of MAPK cascade
positive regulation of MAPK cascade
regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of adenylate cyclase activity
negative regulation of proteolysis
negative regulation of mitotic cell cycle
negative regulation of Ras protein signal transduction
negative regulation of membrane protein ectodomain proteolysis
cellular response to organic substance

Function(s)

protease binding
enzyme inhibitor activity
integrin binding
enzyme activator activity
metalloendopeptidase inhibitor activity
peptidase inhibitor activity
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100039522.mm.1	NM_011594.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100039522.mm.1	NM_011594.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100039522.mm.1	TC1100004157.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100039523.mm.1	NM_011594.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100039523.mm.1	NM_011594.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100039523.mm.1	TC1100004157.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100039524.mm.1	NM_011594.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100039524.mm.1	NM_011594.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100039524.mm.1	TC1100004157.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	908795	-	-