Mm00442497_m1

• Gene Symbol: Mapk14
• Gene Name: mitogen-activated protein kinase 14
• Gene Aliases: CSBP2, Crk1, Csbp1, Mxi2, PRKM14, PRKM15, p38, p38-alpha, p38MAPK, p38a, p38alpha
• Chromosome Location: Chr.17: 28691342 - 28748405 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mapk14
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001168508.1	NP_001161980.1	1 - 2	514		56
	NM_011951.3	NP_036081.1	1 - 2	514		56
GenBank mRNA	AF128892.1	-	1 - 2	412		56
	AK089059.1	-	1 - 2	428		56
	AK133684.1	-	1 - 2	427		56
	BC012235.1	-	1 - 2	514	4195842	56
	BC085303.1	-	1 - 2	490	5389457	56
	D83073.1	-	1 - 2	345		56
	U10871.1	-	1 - 2	412		56

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700000484.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Mapk14

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
cell morphogenesis
cartilage condensation
angiogenesis
placenta development
chondrocyte differentiation
glucose metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
transmembrane receptor protein serine/threonine kinase signaling pathway
skeletal muscle tissue development
positive regulation of gene expression
positive regulation of myotube differentiation
myoblast differentiation involved in skeletal muscle regeneration
phosphorylation
peptidyl-serine phosphorylation
fatty acid oxidation
osteoclast differentiation
positive regulation of cyclase activity
lipopolysaccharide-mediated signaling pathway
response to muramyl dipeptide
response to lipopolysaccharide
intracellular signal transduction
cellular response to vascular endothelial growth factor stimulus
response to muscle stretch
p38MAPK cascade
positive regulation of protein import into nucleus
signal transduction in response to DNA damage
positive regulation of erythrocyte differentiation
positive regulation of myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of glucose import
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
striated muscle cell differentiation
stress-activated MAPK cascade
positive regulation of cardiac muscle cell proliferation
cellular response to lipopolysaccharide
cellular response to ionizing radiation
negative regulation of canonical Wnt signaling pathway
positive regulation of brown fat cell differentiation
stress-induced premature senescence
regulation of cytokine production involved in inflammatory response
positive regulation of myoblast fusion
positive regulation of reactive oxygen species metabolic process

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
protein C-terminus binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
NFAT protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	755610	-	-