Mm00442771_m1

• Gene Symbol: Clu
• Gene Name: clusterin
• Gene Aliases: AI893575, ApoJ, Cli, D14Ucla3, SP-40, Sgp-2, Sgp2, Sugp-2
• Chromosome Location: Chr.14: 65968483 - 65981547 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Clu
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_013492.2	NP_038520.2	5 - 6	1055		77
GenBank mRNA	AF248057.1	-	5 - 6	938		77
	AF248058.1	-	2 - 3	609		77
	BC075668.1	-	5 - 6	884	30550773	77
	D14077.1	-	5 - 6	913		77
	L05670.1	-	5 - 6			77
	L08235.1	-	4 - 5	885		77
	S70244.1	-	4 - 5	849		77

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1400000942.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Clu

Gene Ontology Categories:

Process(es)

cell morphogenesis
microglial cell activation
cell death
positive regulation of cell proliferation
protein import
endocrine pancreas development
central nervous system myelin maintenance
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of protein homooligomerization
positive regulation of tumor necrosis factor production
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of nitric oxide biosynthetic process
positive regulation of cell differentiation
neuron projection morphogenesis
protein stabilization
positive regulation of NF-kappaB transcription factor activity
chaperone-mediated protein complex assembly
response to misfolded protein
chaperone-mediated protein folding
microglial cell proliferation
intrinsic apoptotic signaling pathway
regulation of beta-amyloid clearance
regulation of neuron death
positive regulation of neuron death
positive regulation of beta-amyloid formation
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of beta-amyloid formation
regulation of neuronal signal transduction
positive regulation of tau-protein kinase activity
positive regulation of neurofibrillary tangle assembly
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
ubiquitin protein ligase binding
protein N-terminus binding
misfolded protein binding