Assay Details
Gene Symbol: Tnf | ||||||
---|---|---|---|---|---|---|
Interrogated Sequence | Translated Protein | Exon Boundary | Assay Location | IMAGE Clone ID | Amplicon Length | |
RefSeq | NM_001278601.1 | NP_001265530.1 | 1 - 2 | 352 | 81 | |
NM_013693.3 | NP_038721.1 | 1 - 2 | 352 | 81 | ||
GenBank mRNA | AK153319.1 | - | 1 - 2 | 352 | 81 | |
AK153800.1 | - | 1 - 2 | 352 | 81 | ||
AK154223.1 | - | 1 - 2 | 351 | 81 | ||
AK155964.1 | - | 1 - 2 | 350 | 81 | ||
AY423855.1 | - | 1 - 2 | 85 | 81 | ||
BC117057.1 | - | 1 - 2 | 250 | 40126376 | 81 | |
BC137720.1 | - | 1 - 2 | 251 | 8860739 | 81 | |
BY167004.1 | - | 1 - 2 | 350 | 81 | ||
M11731.1 | - | 1 - 2 | 328 | 81 | ||
M13049.1 | - | 1 - 2 | 348 | 81 | ||
X02611.1 | - | 1 - 2 | 341 | 81 |

More Information
Updated Mapping Information

Set Membership: |
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Matching Ambion siRNAs:
Gene Ontology Categories:
MicroArray Probes:

Citations (101)
Dermal dendritic cells, and not Langerhans cells, play an essential role in inducing an immune response.
- Authors
- Fukunaga A, Khaskhely NM, Sreevidya CS, Byrne SN, Ullrich SE
- Journal
- J Immunol - Page No 3057 (Sat Mar 01 00:00:00 EST 2008)
- Volume (Year)
- 180 (2008)
- Product Usage
- -
Studies on the role of acid sphingomyelinase and ceramide in the regulation of tumor necrosis factor alpha (TNFalpha)-converting enzyme activity and TNFalpha secretion in macrophages.
- Authors
- Rozenova KA, Deevska GM, Karakashian AA, Nikolova-Karakashian MN
- Journal
- J Biol Chem - Page No 21103 (Fri Jul 02 00:00:00 EDT 2010)
- Volume (Year)
- 285 (2010)
- Product Usage
- -
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance.
- Authors
- Tsukumo DM, Carvalho-Filho MA, Carvalheira JB, Prada PO, Hirabara SM, Schenka AA, Araujo EP, Vassallo J, Curi R, Velloso LA, Saad MJ
- Journal
- Diabetes - Page No 1986 (Wed Aug 01 00:00:00 EDT 2007)
- Volume (Year)
- 56 (2007)
- Product Usage
- -
Butter feeding enhances TNF-alpha production from macrophages and lymphocyte adherence in murine small intestinal microvessels.
- Authors
- Fujiyama Y, Hokari R, Miura S, Watanabe C, Komoto S, Oyama T, Kurihara C, Nagata H, Hibi T
- Journal
- J Gastroenterol Hepatol - Page No 1838 (Thu Nov 01 00:00:00 EDT 2007)
- Volume (Year)
- 22 (2007)
- Product Usage
- -
Effects of ultrafine particles-induced oxidative stress on Clara cells in allergic lung inflammation.
- Authors
- Alessandrini F, Weichenmeier I, van Miert E, Takenaka S, Karg E, Blume C, Mempel M, Schulz H, Bernard A, Behrendt H
- Journal
- Part Fibre Toxicol - Page No 11 (Fri Jan 01 00:00:00 EST 2010)
- Volume (Year)
- 7 (2010)
- Product Usage
- -
Fucoxanthin regulates adipocytokine mRNA expression in white adipose tissue of diabetic/obese KK-Ay mice.
- Authors
- Hosokawa M, Miyashita T, Nishikawa S, Emi S, Tsukui T, Beppu F, Okada T, Miyashita K
- Journal
- Arch Biochem Biophys - Page No 17 (Wed Dec 01 00:00:00 EST 2010)
- Volume (Year)
- 504 (2010)
- Product Usage
- -
Comparative analysis of gene expression changes mediated by individual constituents of hemozoin.
- Authors
- Schrimpe AC, Wright DW
- Journal
- Chem Res Toxicol - Page No 433 (Mon Mar 16 00:00:00 EDT 2009)
- Volume (Year)
- 22 (2009)
- Product Usage
- -
MNK kinases regulate multiple TLR pathways and innate proinflammatory cytokines in macrophages.
- Authors
- Rowlett RM, Chrestensen CA, Nyce M, Harp MG, Pelo JW, Cominelli F, Ernst PB, Pizarro TT, Sturgill TW, Worthington MT
- Journal
- Am J Physiol Gastrointest Liver Physiol - Page No G452 (Fri Feb 01 00:00:00 EST 2008)
- Volume (Year)
- 294 (2008)
- Product Usage
- -
Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.
- Authors
- Osborne-Hereford AV, Rogers SW, Gahring LC
- Journal
- J Neuroimmunol - Page No 130 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 193 (2008)
- Product Usage
- -
Shilianhua extract inhibits GSK-3beta and promotes glucose metabolism.
- Authors
- Yin J, Zuberi A, Gao Z, Liu D, Liu Z, Ye J
- Journal
- Am J Physiol Endocrinol Metab - Page No E1275 (Mon Jun 01 00:00:00 EDT 2009)
- Volume (Year)
- 296 (2009)
- Product Usage
- -
Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease.
- Authors
- Johswich K, Martin M, Bleich A, Kracht M, Dittrich-Breiholz O, Gessner JE, Suerbaum S, Wende E, Rheinheimer C, Klos A
- Journal
- Inflamm Bowel Dis - Page No 1812 (Thu Aug 27 00:00:00 EDT 2009)
- Volume (Year)
- 15 (2009)
- Product Usage
- -
IFN-gamma-induced TNF-alpha expression is regulated by interferon regulatory factors 1 and 8 in mouse macrophages.
- Authors
- Vila-del Sol V, Punzon C, Fresno M
- Journal
- J Immunol - Page No 4461 (Wed Oct 01 00:00:00 EDT 2008)
- Volume (Year)
- 181 (2008)
- Product Usage
- -
Active immunization with amyloid-beta 1-42 impairs memory performance through TLR2/4-dependent activation of the innate immune system.
- Authors
- Vollmar P, Kullmann JS, Thilo B, Claussen MC, Rothhammer V, Jacobi H, Sellner J, Nessler S, Korn T, Hemmer B
- Journal
- J Immunol - Page No 6338 (Mon Nov 15 00:00:00 EST 2010)
- Volume (Year)
- 185 (2010)
- Product Usage
- -
Cytokines, signaling pathways, and effector molecules required for the control of Leishmania (Viannia) braziliensis in mice.
- Authors
- Rocha FJ, Schleicher U, Mattner J, Alber G, Bogdan C
- Journal
- Infect Immun - Page No 3823 (Wed Aug 01 00:00:00 EDT 2007)
- Volume (Year)
- 75 (2007)
- Product Usage
- -
Early cytokine expression in mouse sciatic nerve after chronic constriction nerve injury depends on calpain.
- Authors
- Uceyler N, Tscharke A, Sommer C
- Journal
- Brain Behav Immun - Page No 553 (Sun Jul 01 00:00:00 EDT 2007)
- Volume (Year)
- 21 (2007)
- Product Usage
- -
Nitric oxide synthase modulates CFA-induced thermal hyperalgesia through cytokine regulation in mice.
- Authors
- Chen Y, Boettger MK, Reif A, Schmitt A, Uceyler N, Sommer C
- Journal
- Mol Pain - Page No 13 (Fri Jan 01 00:00:00 EST 2010)
- Volume (Year)
- 6 (2010)
- Product Usage
- -
Sickness behavior induced by endotoxin can be mitigated by the dietary soluble fiber, pectin, through up-regulation of IL-4 and Th2 polarization.
- Authors
- Sherry CL, Kim SS, Dilger RN, Bauer LL, Moon ML, Tapping RI, Fahey GC Jr, Tappenden KA, Freund GG
- Journal
- Brain Behav Immun - Page No 631 (Sat May 01 00:00:00 EDT 2010)
- Volume (Year)
- 24 (2010)
- Product Usage
- -
Uncoupling of inflammation and insulin resistance by NF-kappaB in transgenic mice through elevated energy expenditure.
- Authors
- Tang T, Zhang J, Yin J, Staszkiewicz J, Gawronska-Kozak B, Jung DY, Ko HJ, Ong H, Kim JK, Mynatt R, Martin RJ, Keenan M, Gao Z, Ye J
- Journal
- J Biol Chem - Page No 4637 (Fri Feb 12 00:00:00 EST 2010)
- Volume (Year)
- 285 (2010)
- Product Usage
- -
Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume.
- Authors
- Zeidler-Erdely PC, Kashon ML, Battelli LA, Young SH, Erdely A, Roberts JR, Reynolds SH, Antonini JM
- Journal
- Part Fibre Toxicol - Page No 12 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 5 (2008)
- Product Usage
- -
Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators.
- Authors
- Osada Y, Shimizu S, Kumagai T, Yamada S, Kanazawa T
- Journal
- Int J Parasitol - Page No 457 (Sun Mar 01 00:00:00 EST 2009)
- Volume (Year)
- 39 (2009)
- Product Usage
- -
Porphyromonas gingivalis lipids inhibit osteoblastic differentiation and function.
- Authors
- Wang YH, Jiang J, Zhu Q, AlAnezi AZ, Clark RB, Jiang X, Rowe DW, Nichols FC
- Journal
- Infect Immun - Page No 3726 (Wed Sep 01 00:00:00 EDT 2010)
- Volume (Year)
- 78 (2010)
- Product Usage
- -
Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures.
- Authors
- Fu X, Zunich SM, O'Connor JC, Kavelaars A, Dantzer R, Kelley KW
- Journal
- J Neuroinflammation - Page No 43 (Fri Jan 01 00:00:00 EST 2010)
- Volume (Year)
- 7 (2010)
- Product Usage
- -
Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis.
- Authors
- Murphy AC, Lalor SJ, Lynch MA, Mills KH
- Journal
- Brain Behav Immun - Page No 641 (Sat May 01 00:00:00 EDT 2010)
- Volume (Year)
- 24 (2010)
- Product Usage
- -
Mechanisms of sex differences in TNFR2-mediated cardioprotection.
- Authors
- Wang M, Crisostomo PR, Markel TA, Wang Y, Meldrum DR
- Journal
- Circulation - Page No S38 (Tue Sep 30 00:00:00 EDT 2008)
- Volume (Year)
- 118 (2008)
- Product Usage
- -
Cognitive and neuroinflammatory consequences of mild repeated stress are exacerbated in aged mice.
- Authors
- Buchanan JB, Sparkman NL, Chen J, Johnson RW
- Journal
- Psychoneuroendocrinology - Page No 755 (Tue Jul 01 00:00:00 EDT 2008)
- Volume (Year)
- 33 (2008)
- Product Usage
- -
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas.
- Authors
- Park E, Zhu F, Liu B, Xia X, Shen J, Bustos T, Fischer SM, Hu Y
- Journal
- Cancer Res - Page No 9158 (Mon Oct 01 00:00:00 EDT 2007)
- Volume (Year)
- 67 (2007)
- Product Usage
- -
Mutant alpha-synuclein overexpression mediates early proinflammatory activity.
- Authors
- Su X, Federoff HJ, Maguire-Zeiss KA
- Journal
- Neurotox Res - Page No 238 (Thu Oct 01 00:00:00 EDT 2009)
- Volume (Year)
- 16 (2009)
- Product Usage
- -
Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease.
- Authors
- Mori T, Koyama N, Arendash GW, Horikoshi-Sakuraba Y, Tan J, Town T
- Journal
- Glia - Page No 300 (Mon Feb 01 00:00:00 EST 2010)
- Volume (Year)
- 58 (2010)
- Product Usage
- -
Fibrinogen that appears in Bowman's space of proteinuric kidneys in vivo activates podocyte Toll-like receptors 2 and 4 in vitro.
- Authors
- Motojima M, Matsusaka T, Kon V, Ichikawa I
- Journal
- Nephron Exp Nephrol - Page No e39 (Fri Jan 01 00:00:00 EST 2010)
- Volume (Year)
- 114 (2010)
- Product Usage
- -
Effect of HeNe laser irradiation on extracellular matrix deposition and expression of cytokines and chemokines in paracoccidioidomycotic lesions.
- Authors
- Nagib PR, Gameiro J, da Costa TA, Di Gangi R, Ribeiro Jda S, Paulino LC, Verinaud L
- Journal
- Photochem Photobiol - Page No 920 (Thu Jul 01 00:00:00 EDT 2010)
- Volume (Year)
- 86 (2010)
- Product Usage
- -
Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay.
- Authors
- Yin H, Chu A, Li W, Wang B, Shelton F, Otero F, Nguyen DG, Caldwell JS, Chen YA
- Journal
- J Biol Chem - Page No 12328 (Fri May 01 00:00:00 EDT 2009)
- Volume (Year)
- 284 (2009)
- Product Usage
- -
IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis.
- Authors
- Bani-Hani AH, Leslie JA, Asanuma H, Dinarello CA, Campbell MT, Meldrum DR, Zhang H, Hile K, Meldrum KK
- Journal
- Kidney Int - Page No 500 (Tue Sep 01 00:00:00 EDT 2009)
- Volume (Year)
- 76 (2009)
- Product Usage
- -
Deficiency of the negative immune regulator B7-H1 enhances inflammation and neuropathic pain after chronic constriction injury of mouse sciatic nerve.
- Authors
- Uceyler N, Gobel K, Meuth SG, Ortler S, Stoll G, Sommer C, Wiendl H, Kleinschnitz C
- Journal
- Exp Neurol - Page No 153 (Mon Mar 01 00:00:00 EST 2010)
- Volume (Year)
- 222 (2010)
- Product Usage
- -
Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin.
- Authors
- O'Connor JC, Andre C, Wang Y, Lawson MA, Szegedi SS, Lestage J, Castanon N, Kelley KW, Dantzer R
- Journal
- J Neurosci - Page No 4200 (Wed Apr 01 00:00:00 EDT 2009)
- Volume (Year)
- 29 (2009)
- Product Usage
- -
NADPH oxidases regulate CD44 and hyaluronic acid expression in thrombin-treated vascular smooth muscle cells and in atherosclerosis.
- Authors
- Vendrov AE, Madamanchi NR, Niu XL, Molnar KC, Runge M, Szyndralewiez C, Page P, Runge MS
- Journal
- J Biol Chem - Page No 26545 (Fri Aug 20 00:00:00 EDT 2010)
- Volume (Year)
- 285 (2010)
- Product Usage
- -
Early organ-specific endothelial activation during hemorrhagic shock and resuscitation.
- Authors
- van Meurs M, Wulfert FM, Knol AJ, De Haes A, Houwertjes M, Aarts LP, Molema G
- Journal
- Shock - Page No 291 (Fri Feb 01 00:00:00 EST 2008)
- Volume (Year)
- 29 (2008)
- Product Usage
- -
Induction of IDO by bacille Calmette-Guerin is responsible for development of murine depressive-like behavior.
- Authors
- O'Connor JC, Lawson MA, Andre C, Briley EM, Szegedi SS, Lestage J, Castanon N, Herkenham M, Dantzer R, Kelley KW
- Journal
- J Immunol - Page No 3202 (Sun Mar 01 00:00:00 EST 2009)
- Volume (Year)
- 182 (2009)
- Product Usage
- -
Dearterialization of the liver causes intrahepatic cholestasis due to reduced bile transporter expression.
- Authors
- Hoekstra H, Tian Y, Jochum W, Stieger B, Graf R, Porte RJ, Clavien PA
- Journal
- Transplantation - Page No 1159 (Sun Apr 27 00:00:00 EDT 2008)
- Volume (Year)
- 85 (2008)
- Product Usage
- -
Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system.
- Authors
- Chen J, Buchanan JB, Sparkman NL, Godbout JP, Freund GG, Johnson RW
- Journal
- Brain Behav Immun - Page No 301 (Sat Mar 01 00:00:00 EST 2008)
- Volume (Year)
- 22 (2008)
- Product Usage
- -
Staphylococcus Aureus Sepsis and Mitochondrial Accrual of OGG1 DNA Repair Enzyme in Mice.
- Authors
- Bartz RR, Suliman HB, Fu P, Welty-Wolf K, Carraway MS, Macgarvey NC, Withers CM, Sweeney TE, Piantadosi CA
- Journal
- Am J Respir Crit Care Med - Page No (Mon Aug 23 00:00:00 EDT 2010)
- Volume (Year)
- (2010)
- Product Usage
- -
Endogenous interleukin-10 inhibits angiotensin II-induced vascular dysfunction.
- Authors
- Didion SP, Kinzenbaw DA, Schrader LI, Chu Y, Faraci FM
- Journal
- Hypertension - Page No 619 (Tue Sep 01 00:00:00 EDT 2009)
- Volume (Year)
- 54 (2009)
- Product Usage
- -
Placental Effects of Systemic Tumour Necrosis Factor-alpha in an Animal Model of Gestational Diabetes Mellitus.
- Authors
- Bobadilla RA, van Bree R, Vercruysse L, Pijnenborg R, Verhaeghe J
- Journal
- Placenta - Page No 1057 (Wed Dec 01 00:00:00 EST 2010)
- Volume (Year)
- 31 (2010)
- Product Usage
- -
Peripheral lipopolysaccharide administration induces cytokine mRNA expression in the viscera and brain of fever-refractory mice lacking microsomal prostaglandin E synthase-1.
- Authors
- Nilsberth C, Hamzic N, Norell M, Blomqvist A
- Journal
- J Neuroendocrinol - Page No 715 (Sat Aug 01 00:00:00 EDT 2009)
- Volume (Year)
- 21 (2009)
- Product Usage
- -
TLR4 activation mediates kidney ischemia/reperfusion injury.
- Authors
- Wu H, Chen G, Wyburn KR, Yin J, Bertolino P, Eris JM, Alexander SI, Sharland AF, Chadban SJ
- Journal
- J Clin Invest - Page No 2847 (Mon Oct 01 00:00:00 EDT 2007)
- Volume (Year)
- 117 (2007)
- Product Usage
- -
Timed NF-kappaB inhibition in skin reveals dual independent effects on development of HED/EDA and chronic inflammation.
- Authors
- Ulvmar MH, Sur I, Memet S, Toftgard R
- Journal
- J Invest Dermatol - Page No 2584 (Sun Nov 01 00:00:00 EDT 2009)
- Volume (Year)
- 129 (2009)
- Product Usage
- -
Cognitive deficits in interleukin-10-deficient mice after peripheral injection of lipopolysaccharide.
- Authors
- Richwine AF, Sparkman NL, Dilger RN, Buchanan JB, Johnson RW
- Journal
- Brain Behav Immun - Page No 794 (Sat Aug 01 00:00:00 EDT 2009)
- Volume (Year)
- 23 (2009)
- Product Usage
- -
Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice.
- Authors
- Geboes L, Dumoutier L, Kelchtermans H, Schurgers E, Mitera T, Renauld JC, Matthys P
- Journal
- Arthritis Rheum - Page No 390 (Sun Feb 01 00:00:00 EST 2009)
- Volume (Year)
- 60 (2009)
- Product Usage
- -
Interleukin-6 facilitates lipopolysaccharide-induced disruption in working memory and expression of other proinflammatory cytokines in hippocampal neuronal cell layers.
- Authors
- Sparkman NL, Buchanan JB, Heyen JR, Chen J, Beverly JL, Johnson RW
- Journal
- J Neurosci - Page No 10709 (Wed Oct 18 00:00:00 EDT 2006)
- Volume (Year)
- 26 (2006)
- Product Usage
- -
Site-specific inhibition of glomerulonephritis progression by targeted delivery of dexamethasone to glomerular endothelium.
- Authors
- Asgeirsdottir SA, Kamps JA, Bakker HI, Zwiers PJ, Heeringa P, van der Weide K, van Goor H, Petersen AH, Morselt H, Moorlag HE, Steenbergen E, Kallenberg CG, Molema G
- Journal
- Mol Pharmacol - Page No 121 (Sun Jul 01 00:00:00 EDT 2007)
- Volume (Year)
- 72 (2007)
- Product Usage
- -
Purple carrot (Daucus carota L.) polyacetylenes decrease lipopolysaccharide-induced expression of inflammatory proteins in macrophage and endothelial cells.
- Authors
- Metzger BT, Barnes DM, Reed JD
- Journal
- J Agric Food Chem - Page No 3554 (Wed May 28 00:00:00 EDT 2008)
- Volume (Year)
- 56 (2008)
- Product Usage
- -
Both TLR2 and TLR4 are required for the effective immune response in Staphylococcus aureus-induced experimental murine brain abscess.
- Authors
- Stenzel W, Soltek S, Sanchez-Ruiz M, Akira S, Miletic H, Schluter D, Deckert M
- Journal
- Am J Pathol - Page No 132 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 172 (2008)
- Product Usage
- -
Inhibition of bradykinin receptor B1 protects mice from focal brain injury by reducing blood-brain barrier leakage and inflammation.
- Authors
- Raslan F, Schwarz T, Meuth SG, Austinat M, Bader M, Renne T, Roosen K, Stoll G, Siren AL, Kleinschnitz C
- Journal
- J Cereb Blood Flow Metab - Page No 1477 (Sun Aug 01 00:00:00 EDT 2010)
- Volume (Year)
- 30 (2010)
- Product Usage
- -
Interleukin-10 overexpression promotes Fas-ligand-dependent chronic macrophage-mediated demyelinating polyneuropathy.
- Authors
- Dace DS, Khan AA, Stark JL, Kelly J, Cross AH, Apte RS
- Journal
- Plos One - Page No e7121 (Thu Jan 01 00:00:00 EST 2009)
- Volume (Year)
- 4 (2009)
- Product Usage
- -
Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier.
- Authors
- Pawar RD, Castrezana-Lopez L, Allam R, Kulkarni OP, Segerer S, Radomska E, Meyer TN, Schwesinger CM, Akis N, Grone HJ, Anders HJ
- Journal
- Immunology - Page No e206 (Tue Sep 01 00:00:00 EDT 2009)
- Volume (Year)
- 128 (2009)
- Product Usage
- -
Forced IFIT-2 expression represses LPS induced TNF-alpha expression at posttranscriptional levels.
- Authors
- Berchtold S, Manncke B, Klenk J, Geisel J, Autenrieth IB, Bohn E
- Journal
- Bmc Immunol - Page No 75 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 9 (2008)
- Product Usage
- -
Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling.
- Authors
- Osuchowski MF, Edwards GL, Sharma RP
- Journal
- Neurotoxicology - Page No 211 (Tue Mar 01 00:00:00 EST 2005)
- Volume (Year)
- 26 (2005)
- Product Usage
- -
Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice.
- Authors
- Sasaki R, Nishimura N, Hoshino H, Isa Y, Kadowaki M, Ichi T, Tanaka A, Nishiumi S, Fukuda I, Ashida H, Horio F, Tsuda T
- Journal
- Biochem Pharmacol - Page No 1619 (Mon Dec 03 00:00:00 EST 2007)
- Volume (Year)
- 74 (2007)
- Product Usage
- -
Soluble lymphotoxin is an important effector molecule in GVHD and GVL.
- Authors
- Markey KA, Burman AC, Banovic T, Kuns RD, Raffelt NC, Rowe V, Olver SD, Don AL, Morris ES, Pettit AR, Wilson YA, Robb RJ, Randall LM, Korner H, Engwerda CR, Clouston AD, Macdonald KP, Hill GR
- Journal
- Blood - Page No 122 (Thu Jan 07 00:00:00 EST 2010)
- Volume (Year)
- 115 (2010)
- Product Usage
- -
Psychological stress reactivates dextran sulfate sodium-induced chronic colitis in mice.
- Authors
- Melgar S, Engstrom K, Jagervall A, Martinez V
- Journal
- Stress - Page No 348 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 11 (2008)
- Product Usage
- -
alpha-Tocopherol and selenium facilitate recovery from lipopolysaccharide-induced sickness in aged mice.
- Authors
- Berg BM, Godbout JP, Chen J, Kelley KW, Johnson RW
- Journal
- J Nutr - Page No 1157 (Sun May 01 00:00:00 EDT 2005)
- Volume (Year)
- 135 (2005)
- Product Usage
- -
Decreased alveolar macrophage apoptosis is associated with increased pulmonary inflammation in a murine model of pneumococcal pneumonia.
- Authors
- Marriott HM, Hellewell PG, Cross SS, Ince PG, Whyte MK, Dockrell DH
- Journal
- J Immunol - Page No 6480 (Wed Nov 01 00:00:00 EST 2006)
- Volume (Year)
- 177 (2006)
- Product Usage
- -
Small interfering RNA (siRNA) delivery into murine bone marrow-derived macrophages by electroporation.
- Authors
- Wiese M, Castiglione K, Hensel M, Schleicher U, Bogdan C, Jantsch J
- Journal
- J Immunol Methods - Page No 102 (Sun Feb 28 00:00:00 EST 2010)
- Volume (Year)
- 353 (2010)
- Product Usage
- -
Architectural changes to CA1 pyramidal neurons in adult and aged mice after peripheral immune stimulation.
- Authors
- Richwine AF, Parkin AO, Buchanan JB, Chen J, Markham JA, Juraska JM, Johnson RW
- Journal
- Psychoneuroendocrinology - Page No 1369 (Sat Nov 01 00:00:00 EDT 2008)
- Volume (Year)
- 33 (2008)
- Product Usage
- -
Adipose tissue in offspring of Lepr(db/+) mice: early-life environment vs. genotype.
- Authors
- Lambin S, van Bree R, Caluwaerts S, Vercruysse L, Vergote I, Verhaeghe J
- Journal
- Am J Physiol Endocrinol Metab - Page No E262 (Mon Jan 01 00:00:00 EST 2007)
- Volume (Year)
- 292 (2007)
- Product Usage
- -
Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice.
- Authors
- Kelly J, Ali Khan A, Yin J, Ferguson TA, Apte RS
- Journal
- J Clin Invest - Page No 3421 (Thu Nov 01 00:00:00 EDT 2007)
- Volume (Year)
- 117 (2007)
- Product Usage
- -
5-lipoxygenase activating protein signals adipose tissue inflammation and lipid dysfunction in experimental obesity.
- Authors
- Horrillo R, Gonzalez-Periz A, Martinez-Clemente M, Lopez-Parra M, Ferre N, Titos E, Moran-Salvador E, Deulofeu R, Arroyo V, Claria J
- Journal
- J Immunol - Page No 3978 (Thu Apr 01 00:00:00 EDT 2010)
- Volume (Year)
- 184 (2010)
- Product Usage
- -
Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis.
- Authors
- Centonze D, Muzio L, Rossi S, Cavasinni F, De Chiara V, Bergami A, Musella A, D'Amelio M, Cavallucci V, Martorana A, Bergamaschi A, Cencioni MT, Diamantini A, Butti E, Comi G, Bernardi G, Cecconi F, Battistini L, Furlan R, Martino G
- Journal
- J Neurosci - Page No 3442 (Wed Mar 18 00:00:00 EDT 2009)
- Volume (Year)
- 29 (2009)
- Product Usage
- -
Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury.
- Authors
- Frenkel D, Pachori AS, Zhang L, Dembinsky-Vaknin A, Farfara D, Petrovic-Stojkovic S, Dzau VJ, Weiner HL
- Journal
- Int Immunol - Page No 817 (Wed Jul 01 00:00:00 EDT 2009)
- Volume (Year)
- 21 (2009)
- Product Usage
- -
Regulation of the inflammatory response to Staphylococcus aureus-induced brain abscess by interleukin-10.
- Authors
- Stenzel W, Dahm J, Sanchez-Ruiz M, Miletic H, Hermann M, Courts C, Schwindt H, Utermohlen O, Schluter D, Deckert M
- Journal
- J Neuropathol Exp Neurol - Page No 1046 (Thu Dec 01 00:00:00 EST 2005)
- Volume (Year)
- 64 (2005)
- Product Usage
- -
Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.
- Authors
- Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, Garlanda C, Mantovani A, Anders HJ
- Journal
- J Exp Med - Page No 1879 (Mon Aug 04 00:00:00 EDT 2008)
- Volume (Year)
- 205 (2008)
- Product Usage
- -
Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses.
- Authors
- Allam R, Pawar RD, Kulkarni OP, Hornung V, Hartmann G, Segerer S, Akira S, Endres S, Anders HJ
- Journal
- Eur J Immunol - Page No 3487 (Mon Dec 01 00:00:00 EST 2008)
- Volume (Year)
- 38 (2008)
- Product Usage
- -
Inhibition of COX 1 and 2 prior to renal ischemia/reperfusion injury decreases the development of fibrosis.
- Authors
- Feitoza CQ, Goncalves GM, Semedo P, Cenedeze MA, Pinheiro HS, Beraldo FC, dos Santos OF, Teixeira Vde P, dos Reis MA, Mazzali M, Pacheco-Silva A, Camara NO
- Journal
- Mol Med - Page No 724 (Sat Nov 01 00:00:00 EDT 2008)
- Volume (Year)
- 14 (2008)
- Product Usage
- -
Curcumin attenuates elastase- and cigarette smoke-induced pulmonary emphysema in mice.
- Authors
- Suzuki M, Betsuyaku T, Ito Y, Nagai K, Odajima N, Moriyama C, Nasuhara Y, Nishimura M
- Journal
- Am J Physiol Lung Cell Mol Physiol - Page No L614 (Wed Apr 01 00:00:00 EDT 2009)
- Volume (Year)
- 296 (2009)
- Product Usage
- -
Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration.
- Authors
- Andre C, O'Connor JC, Kelley KW, Lestage J, Dantzer R, Castanon N
- Journal
- J Neuroimmunol - Page No 90 (Sat Aug 30 00:00:00 EDT 2008)
- Volume (Year)
- 200 (2008)
- Product Usage
- -
TLR4-mediated induction of TLR2 signaling is critical in the pathogenesis and resolution of otitis media.
- Authors
- Leichtle A, Hernandez M, Pak K, Yamasaki K, Cheng CF, Webster NJ, Ryan AF, Wasserman SI
- Journal
- Innate Immun - Page No 205 (Sat Aug 01 00:00:00 EDT 2009)
- Volume (Year)
- 15 (2009)
- Product Usage
- -
CD8 T cells producing IL-17 and IFN-gamma initiate the innate immune response required for responses to antigen skin challenge.
- Authors
- Kish DD, Li X, Fairchild RL
- Journal
- J Immunol - Page No 5949 (Fri May 15 00:00:00 EDT 2009)
- Volume (Year)
- 182 (2009)
- Product Usage
- -
Role of IFN-gamma and IL-6 in a protective immune response to Yersinia enterocolitica in mice.
- Authors
- Matteoli G, Fahl E, Warnke P, Muller S, Bonin M, Autenrieth IB, Bohn E
- Journal
- Bmc Microbiol - Page No 153 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 8 (2008)
- Product Usage
- -
Attenuation of folic acid-induced renal inflammatory injury in platelet-activating factor receptor-deficient mice.
- Authors
- Doi K, Okamoto K, Negishi K, Suzuki Y, Nakao A, Fujita T, Toda A, Yokomizo T, Kita Y, Kihara Y, Ishii S, Shimizu T, Noiri E
- Journal
- Am J Pathol - Page No 1413 (Mon May 01 00:00:00 EDT 2006)
- Volume (Year)
- 168 (2006)
- Product Usage
- -
Lipopolysaccharide induces adipose differentiation-related protein expression and lipid accumulation in the liver through inhibition of fatty acid oxidation in mice.
- Authors
- Ohhira M, Motomura W, Fukuda M, Yoshizaki T, Takahashi N, Tanno S, Wakamiya N, Kohgo Y, Kumei S, Okumura T
- Journal
- J Gastroenterol - Page No 969 (Sat Dec 01 00:00:00 EST 2007)
- Volume (Year)
- 42 (2007)
- Product Usage
- -
PKC412 (CGP41251) modulates the proliferation and lipopolysaccharide-induced inflammatory responses of RAW 264.7 macrophages.
- Authors
- Miyatake K, Inoue H, Hashimoto K, Takaku H, Takata Y, Nakano S, Yasui N, Itakura M
- Journal
- Biochem Biophys Res Commun - Page No 115 (Fri Aug 17 00:00:00 EDT 2007)
- Volume (Year)
- 360 (2007)
- Product Usage
- -
Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis.
- Authors
- Montrose DC, Horelik NA, Madigan JP, Stoner GD, Wang LS, Bruno RS, Park HJ, Giardina C, Rosenberg DW
- Journal
- Carcinogenesis - Page No (Tue Nov 23 00:00:00 EST 2010)
- Volume (Year)
- (2010)
- Product Usage
- -
Korean red ginseng extract ameliorates skin lesions in NC/Nga mice: An atopic dermatitis model.
- Authors
- Lee JH, Cho SH
- Journal
- J Ethnopharmacol - Page No (Sat Nov 20 00:00:00 EST 2010)
- Volume (Year)
- (2010)
- Product Usage
- -
Administration of neural precursor cells ameliorates renal ischemia-reperfusion injury.
- Authors
- Wang PH, Schwindt TT, Barnabe GF, Motta FL, Semedo P, Beraldo FC, Mazzali M, Dos Reis MA, Teixeira Vde P, Pacheco-Silva A, Mello LE, Camara NO
- Journal
- Nephron Exp Nephrol - Page No e20 (Thu Jan 01 00:00:00 EST 2009)
- Volume (Year)
- 112 (2009)
- Product Usage
- -
Herpes simplex virus infects skin gamma delta T cells before Langerhans cells and impedes migration of infected Langerhans cells by inducing apoptosis and blocking E-cadherin downregulation.
- Authors
- Puttur FK, Fernandez MA, White R, Roediger B, Cunningham AL, Weninger W, Jones CA
- Journal
- J Immunol - Page No 477 (Thu Jul 01 00:00:00 EDT 2010)
- Volume (Year)
- 185 (2010)
- Product Usage
- -
Comprehensive mRNA profiling of lipid-related genes in microglia and macrophages using taqman arrays.
- Authors
- Mauerer R, Walczak Y, Langmann T
- Journal
- Methods Mol Biol - Page No 187 (Thu Jan 01 00:00:00 EST 2009)
- Volume (Year)
- 580 (2009)
- Product Usage
- -
Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model.
- Authors
- Shindo N, Fujisawa T, Sugimoto K, Nojima K, Oze-Fukai A, Yoshikawa Y, Wang X, Yasuda O, Ikegami H, Rakugi H
- Journal
- J Hepatol - Page No 903 (Tue Jun 01 00:00:00 EDT 2010)
- Volume (Year)
- 52 (2010)
- Product Usage
- -
Bronchiolar chemokine expression is different after single versus repeated cigarette smoke exposure.
- Authors
- Betsuyaku T, Hamamura I, Hata J, Takahashi H, Mitsuhashi H, Adair-Kirk TL, Senior RM, Nishimura M
- Journal
- Respir Res - Page No 7 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 9 (2008)
- Product Usage
- -
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity.
- Authors
- Milanski M, Degasperi G, Coope A, Morari J, Denis R, Cintra DE, Tsukumo DM, Anhe G, Amaral ME, Takahashi HK, Curi R, Oliveira HC, Carvalheira JB, Bordin S, Saad MJ, Velloso LA
- Journal
- J Neurosci - Page No 359 (Wed Jan 14 00:00:00 EST 2009)
- Volume (Year)
- 29 (2009)
- Product Usage
- -
Conditional Deletion of Abca3 in Alveolar Type II Cells Alters Surfactant Homeostasis in Newborn and Adult Mice.
- Authors
- Besnard V, Matsuzaki Y, Clark JC, Xu Y, Wert SE, Ikegami M, Stahlman MT, Weaver TE, Hunt AN, Postle AD, Whitsett JA
- Journal
- Am J Physiol Lung Cell Mol Physiol - Page No (Fri Feb 26 00:00:00 EST 2010)
- Volume (Year)
- (2010)
- Product Usage
- -
Intra-colonic administration of the TLR7 agonist R-848 induces an acute local and systemic inflammation in mice.
- Authors
- Karlsson A, Jagervall K, Utkovic H, Karlsson L, Rehnstrom E, Fredin MF, Gillberg PG, Jansson L, Michaelsson E, Melgar S
- Journal
- Biochem Biophys Res Commun - Page No 242 (Fri Mar 07 00:00:00 EST 2008)
- Volume (Year)
- 367 (2008)
- Product Usage
- -
Suppression of stroke-induced progenitor proliferation in adult subventricular zone by tumor necrosis factor receptor 1.
- Authors
- Iosif RE, Ahlenius H, Ekdahl CT, Darsalia V, Thored P, Jovinge S, Kokaia Z, Lindvall O
- Journal
- J Cereb Blood Flow Metab - Page No 1574 (Mon Sep 01 00:00:00 EDT 2008)
- Volume (Year)
- 28 (2008)
- Product Usage
- -
Phthalate ester-induced thymic stromal lymphopoietin mediates allergic dermatitis in mice.
- Authors
- Shigeno T, Katakuse M, Fujita T, Mukoyama Y, Watanabe H
- Journal
- Immunology - Page No e849 (Tue Sep 01 00:00:00 EDT 2009)
- Volume (Year)
- 128 (2009)
- Product Usage
- -
Tumor necrosis factor alpha-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis.
- Authors
- Inoue A, Matsumoto I, Tanaka Y, Iwanami K, Kanamori A, Ochiai N, Goto D, Ito S, Sumida T
- Journal
- Arthritis Res Ther - Page No R118 (Thu Jan 01 00:00:00 EST 2009)
- Volume (Year)
- 11 (2009)
- Product Usage
- -
IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages.
- Authors
- O'Connell AE, Kerepesi LA, Vandergrift GL, Herbert DR, VAN Winkle TJ, Hooper DC, Pearce EJ, Abraham D
- Journal
- Parasite Immunol - Page No 741 (Tue Dec 01 00:00:00 EST 2009)
- Volume (Year)
- 31 (2009)
- Product Usage
- -
Chronic mouse model of TMA-induced contact hypersensitivity.
- Authors
- Schneider C, Docke WD, Zollner TM, Rose L
- Journal
- J Invest Dermatol - Page No 899 (Wed Apr 01 00:00:00 EDT 2009)
- Volume (Year)
- 129 (2009)
- Product Usage
- -
Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.
- Authors
- Gao Z, Yin J, Zhang J, He Q, McGuinness OP, Ye J
- Journal
- J Biol Chem - Page No 18368 (Fri Jul 03 00:00:00 EDT 2009)
- Volume (Year)
- 284 (2009)
- Product Usage
- -
Suppression of proinflammatory cytokine production in macrophages by lansoprazole.
- Authors
- Hinoki A, Yoshimura K, Fujita K, Akita M, Ikeda R, Nagashima M, Nomura M, Satomi A
- Journal
- Pediatr Surg Int - Page No 915 (Wed Nov 01 00:00:00 EST 2006)
- Volume (Year)
- 22 (2006)
- Product Usage
- -
Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis.
- Authors
- Popivanova BK, Kitamura K, Wu Y, Kondo T, Kagaya T, Kaneko S, Oshima M, Fujii C, Mukaida N
- Journal
- J Clin Invest - Page No 560 (Fri Feb 01 00:00:00 EST 2008)
- Volume (Year)
- 118 (2008)
- Product Usage
- -
Novel model of TH2-polarized chronic ileitis: the SAMP1 mouse.
- Authors
- McNamee EN, Wermers JD, Masterson JC, Collins CB, Lebsack MD, Fillon S, Robinson ZD, Grenawalt J, Lee JJ, Jedlicka P, Furuta GT, Rivera-Nieves J
- Journal
- Inflamm Bowel Dis - Page No 743 (Sat May 01 00:00:00 EDT 2010)
- Volume (Year)
- 16 (2010)
- Product Usage
- -
Subtherapeutic dose of pioglitazone reduces expression of inflammatory adipokines in db/db mice.
- Authors
- Mohapatra J, Sharma M, Singh S, Chatterjee A, Swain P, Balaraman R, Patel PR, Jain MR
- Journal
- Pharmacology - Page No 203 (Thu Jan 01 00:00:00 EST 2009)
- Volume (Year)
- 84 (2009)
- Product Usage
- -
The antidepressant venlafaxine ameliorates murine experimental autoimmune encephalomyelitis by suppression of pro-inflammatory cytokines.
- Authors
- Vollmar P, Nessler S, Kalluri SR, Hartung HP, Hemmer B
- Journal
- Int J Neuropsychopharmacol - Page No 525 (Fri May 01 00:00:00 EDT 2009)
- Volume (Year)
- 12 (2009)
- Product Usage
- -
