Mm00443448_m1

• Gene Symbol: Nr1h3
• Gene Name: nuclear receptor subfamily 1, group H, member 3
• Gene Aliases: AU018371, LXR, RLD1, Unr1
• Chromosome Location: Chr.2: 91184061 - 91202834 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Nr1h3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001177730.1	NP_001171201.1	1 - 2	151		88
GenBank mRNA	AK143904.1	-	1 - 2	85		88
	AY195870.1	-	1 - 2	151		88
	AY195871.1	-	1 - 2	151		88
	BC012646.1	-	1 - 2	92	4163109	88

More Information

Additional Information:

This assay is in the 5'UTR region of the AK143904.1, AY195870.1, AY195871.1, BC012646.1, NM_001177730.1 transcripts.

• Set Membership: Amplicon length between 86 and 100, Nuclear Receptor, Mammalian Gene Collection, Mus musculus, 1700, Probe spans exons

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
fatty acid biosynthetic process
positive regulation of triglyceride biosynthetic process
positive regulation of receptor biosynthetic process
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
intracellular receptor signaling pathway
positive regulation of cellular protein metabolic process
negative regulation of lipid transport
positive regulation of cholesterol transport
response to progesterone
positive regulation of toll-like receptor 4 signaling pathway
cholesterol homeostasis
negative regulation of macrophage activation
apoptotic cell clearance
steroid hormone mediated signaling pathway
cellular lipid metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of pinocytosis
negative regulation of inflammatory response
positive regulation of lipoprotein lipase activity
lipid homeostasis
sterol homeostasis
triglyceride homeostasis
cellular response to lipopolysaccharide
negative regulation of pancreatic juice secretion
negative regulation of secretion of lysosomal enzymes
regulation of cholesterol homeostasis
positive regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
sterol response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
retinoid X receptor binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0200034420.mm.1	NM_001177730.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034420.mm.1	NM_001177730.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034420.mm.1	TC0200004109.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0200034416.mm.1	NM_001177730.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034416.mm.1	NM_001177730.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034416.mm.1	NM_013839.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034416.mm.1	NM_013839.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034416.mm.1	TC0200004109.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0200034412.mm.1	NM_001177730.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034412.mm.1	NM_001177730.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034412.mm.1	NM_013839.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034412.mm.1	NM_013839.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0200034412.mm.1	TC0200004109.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	556716	-	-