Mm00443836_g1

• Gene Symbol: Chek2
• Gene Name: checkpoint kinase 2
• Gene Aliases: CHK2, Cds1, HUCDS1, Rad53
• Chromosome Location: Chr.5: 110839791 - 110874140 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Chek2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_016681.3	NP_057890.1	3 - 4	496		91
GenBank mRNA	AF086905.1	-	2 - 3	457		91
	AK044913.1	-	3 - 4	497		91
	AK170235.1	-	3 - 4	531		91
	BC056617.1	-	3 - 4	520	4977960	91

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Chek2

Gene Ontology Categories:

Process(es)

DNA damage checkpoint signaling
G2/M transition of mitotic cell cycle
mitotic cell cycle
DNA repair
double-strand break repair
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
cell cycle
intrinsic apoptotic signaling pathway in response to DNA damage
response to gamma radiation
phosphorylation
mitotic intra-S DNA damage checkpoint signaling
regulation of protein catabolic process
signal transduction in response to DNA damage
cellular protein catabolic process
positive regulation of transcription, DNA-templated
protein autophosphorylation
protein stabilization
cell division
mitotic spindle assembly

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
metal ion binding