Mm00443839_m1 Best Coverage

• Gene Symbol: Chek2
• Gene Name: checkpoint kinase 2
• Gene Aliases: CHK2, Cds1, HUCDS1, Rad53
• Chromosome Location: Chr.5: 110839791 - 110874140 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Chek2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_016681.3	NP_057890.1	7 - 8	900		122
GenBank mRNA	AF086905.1	-	6 - 7	861		122
	AK044913.1	-	7 - 8	901		122
	AK170235.1	-	6 - 7	844		122
	BC056617.1	-	7 - 8	924	4977960	122

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500001152.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Recommended Assay, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Chek2

Gene Ontology Categories:

Process(es)

DNA damage checkpoint signaling
G2/M transition of mitotic cell cycle
mitotic cell cycle
DNA repair
double-strand break repair
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
cell cycle
intrinsic apoptotic signaling pathway in response to DNA damage
response to gamma radiation
phosphorylation
mitotic intra-S DNA damage checkpoint signaling
regulation of protein catabolic process
signal transduction in response to DNA damage
cellular protein catabolic process
positive regulation of transcription, DNA-templated
protein autophosphorylation
protein stabilization
cell division
mitotic spindle assembly

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500009899.mm.1	TC0500001152.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500009899.mm.1	NM_016681.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500009899.mm.1	NM_016681.3	Refseq