Mm00444945_g1

• Gene Symbol: Ripk3
• Gene Name: receptor-interacting serine-threonine kinase 3
• Gene Aliases: 2610528K09Rik, AW107945, Rip3
• Chromosome Location: Chr.14: 55784995 - 55788857 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ripk3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001164107.1	NP_001157579.1	7 - 8	1126		95
	NM_001164108.1	NP_001157580.1	7 - 8	1224		95
	NM_019955.2	NP_064339.2	7 - 8	1143		95
GenBank mRNA	AA270784.1	-	2 - 3	233		95
	AF178953.1	-	7 - 8	1072		95
	AK012177.1	-	7 - 8	1116		95
	AK154505.1	-	7 - 8	1136		95
	BC029210.1	-	7 - 8	1094	3590770	95

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1400002103.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Kinase, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ripk3

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

regulation of T cell mediated cytotoxicity
regulation of adaptive immune response
protein phosphorylation
I-kappaB kinase/NF-kappaB signaling
positive regulation of phosphatase activity
programmed cell death
viral process
phosphorylation
signal transduction by protein phosphorylation
activation of protein kinase activity
regulation of interferon-gamma production
T cell differentiation in thymus
NIK/NF-kappaB signaling
T cell homeostasis
regulation of activated T cell proliferation
protein autophosphorylation
lymph node development
spleen development
thymus development
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
protein heterooligomerization
positive regulation of transferase activity
positive regulation of ligase activity
positive regulation of oxidoreductase activity
positive regulation of necroptotic process
regulation of activation-induced cell death of T cells
necroptotic process
positive regulation of protein deacetylation
amyloid fibril formation
regulation of reactive oxygen species metabolic process
positive regulation of reactive oxygen species metabolic process
regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
NF-kappaB-inducing kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein complex binding
identical protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1400016205.mm.1	NM_001164107.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1400016205.mm.1	NM_001164107.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1400016205.mm.1	NM_001164108.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1400016205.mm.1	NM_001164108.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1400016205.mm.1	NM_019955.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1400016205.mm.1	NM_019955.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1400016205.mm.1	TC1400002103.mm.1	MTA TC