Assay Details

Gene Symbol: Tbp
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_013684.3	NP_038712.3	4 - 5	768		73
GenBank mRNA	BC012685.1	-	6 - 7	1004	3498542	73
	BC016476.1	-	4 - 5	746	3584341	73
	BC050136.1	-	4 - 5	719	30020603	73
	D01034.1	-	3 - 4	585		73
	U63933.1	-	5 - 6	774		73

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700000183.mm.1

Set Membership:

Ambion siRNA available

Amplicon length between 71 and 85

Mammalian Gene Collection

Endogenous Controls

Mus musculus

Mouse Endogenous Controls

Inventoried

Mouse_Endogenous_Controls

Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Tbp

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Function(s) Process(es)

Citations (31)

NPM-ALK-dependent expression of the transcription factor CCAAT/enhancer binding protein beta in ALK-positive anaplastic large cell lymphoma.

Authors: Quintanilla-Martinez L, Pittaluga S, Miething C, Klier M, Rudelius M, Davies-Hill T, Anastasov N, Martinez A, Vivero A, Duyster J, Jaffe ES, Fend F, Raffeld M
Journal: Blood - Page No 2029 (Fri Sep 15 00:00:00 EDT 2006)
Volume (Year): 108 (2006)
Product Usage: -

Governing cell lineage formation in cloned mouse embryos.

Authors: Balbach ST, Esteves TC, Brink T, Gentile L, McLaughlin KJ, Adjaye JA, Boiani M
Journal: Dev Biol - Page No 71 (Thu Jul 01 00:00:00 EDT 2010)
Volume (Year): 343 (2010)
Product Usage: -

Development of lupus nephritis is associated with qualitative changes in the glomerular collagen IV matrix composition.

Authors: Tveita AA, Ninomiya Y, Sado Y, Rekvig OP, Zykova SN
Journal: Lupus - Page No 355 (Wed Apr 01 00:00:00 EDT 2009)
Volume (Year): 18 (2009)
Product Usage: -

A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis.

Authors: Sher RB, Aoyama C, Huebsch KA, Ji S, Kerner J, Yang Y, Frankel WN, Hoppel CL, Wood PA, Vance DE, Cox GA
Journal: J Biol Chem - Page No 4938 (Fri Feb 24 00:00:00 EST 2006)
Volume (Year): 281 (2006)
Product Usage: -

Liver X receptor agonism promotes articular inflammation in murine collagen-induced arthritis.

Authors: Asquith DL, Miller AM, Hueber AJ, McKinnon HJ, Sattar N, Graham GJ, McInnes IB
Journal: Arthritis Rheum - Page No 2655 (Tue Sep 01 00:00:00 EDT 2009)
Volume (Year): 60 (2009)
Product Usage: -

IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination.

Authors: Freude S, Leeser U, Muller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Kohler C, Schroder H, Krone W, Bruning JC, Schubert M
Journal: J Neurochem - Page No 907 (Sat Nov 01 00:00:00 EDT 2008)
Volume (Year): 107 (2008)
Product Usage: -

Expression analysis of 6p22 genomic gain in retinoblastoma.

Authors: Orlic M, Spencer CE, Wang L, Gallie BL
Journal: Genes Chromosomes Cancer - Page No 72 (Sun Jan 01 00:00:00 EST 2006)
Volume (Year): 45 (2006)
Product Usage: -

Deposition of chromatin-IgG complexes in skin of nephritic MRL-lpr/lpr mice is associated with increased local matrix metalloprotease activities.

Authors: Hedberg A, Fismen S, Fenton KA, Mortensen ES, Rekvig OP
Journal: Exp Dermatol - Page No e265 (Sun Aug 01 00:00:00 EDT 2010)
Volume (Year): 19 (2010)
Product Usage: -

Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice.

Authors: Fenton K, Fismen S, Hedberg A, Seredkina N, Fenton C, Mortensen ES, Rekvig OP
Journal: Plos One - Page No e8474 (Thu Jan 01 00:00:00 EST 2009)
Volume (Year): 4 (2009)
Product Usage: -

Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders.

Authors: Mercader JM, Saus E, Aguera Z, Bayes M, Boni C, Carreras A, Cellini E, de Cid R, Dierssen M, Escaramis G, Fernandez-Aranda F, Forcano L, Gallego X, Gonzalez JR, Gorwood P, Hebebrand J, Hinney A, Nacmias B, Puig A, Ribases M, Ricca V, Romo L, Sorbi S, Versini A, Gratacos M, Estivill X
Journal: Hum Mol Genet - Page No 1234 (Thu May 01 00:00:00 EDT 2008)
Volume (Year): 17 (2008)
Product Usage: -

In vivo characterization of estrogen receptor modulators with reduced genomic versus nongenomic activity in vitro.

Authors: Otto C, Fuchs I, Altmann H, Klewer M, Schwarz G, Bohlmann R, Nguyen D, Zorn L, Vonk R, Prelle K, Osterman T, Malmstrom C, Fritzemeier KH
Journal: J Steroid Biochem Mol Biol - Page No 95 (Tue Jul 01 00:00:00 EDT 2008)
Volume (Year): 111 (2008)
Product Usage: -

Metabolic bioactivation of oestradiol-17beta (E2beta) in mouse colon epithelial cells bearing ApcMin mutation.

Authors: Bellocq D, Molina J, Rathahao-Paris E, Tache S, Pierre F, Paris A
Journal: Steroids - Page No 665 (Fri Oct 01 00:00:00 EDT 2010)
Volume (Year): 75 (2010)
Product Usage: -

Oxidised LDL up-regulate CD36 expression by the Nrf2 pathway in 3T3-L1 preadipocytes.

Authors: D'Archivio M, Scazzocchio B, Filesi C, Vari R, Maggiorella MT, Sernicola L, Santangelo C, Giovannini C, Masella R
Journal: Febs Lett - Page No 2291 (Wed Jun 25 00:00:00 EDT 2008)
Volume (Year): 582 (2008)
Product Usage: -

Palifermin mediates immunoregulatory effects in addition to its cytoprotective effects in mice with acute graft-versus-host disease.

Authors: Ellison CA, Makar BM, Wiseman JM, Gheorghiu I, Taniguchi M, Gartner JG
Journal: J Clin Immunol - Page No 600 (Mon Sep 01 00:00:00 EDT 2008)
Volume (Year): 28 (2008)
Product Usage: -

Cooperative role of NF-{kappa}B and poly(ADP-ribose) polymerase 1 (PARP-1) in the TNF-induced inhibition of PHEX expression in osteoblasts.

Authors: Majewski PM, Thurston RD, Ramalingam R, Kiela PR, Ghishan FK
Journal: J Biol Chem - Page No 34828 (Fri Nov 05 00:00:00 EDT 2010)
Volume (Year): 285 (2010)
Product Usage: -

Microarray analysis of gene expression of mouse hepatocytes of different ploidy.

Authors: Lu P, Prost S, Caldwell H, Tugwood JD, Betton GR, Harrison DJ
Journal: Mamm Genome - Page No 617 (Sat Sep 01 00:00:00 EDT 2007)
Volume (Year): 18 (2007)
Product Usage: -

An insulator embedded in the chicken {alpha}-globin locus regulates chromatin domain configuration and differential gene expression.

Authors: Furlan-Magaril M, Rebollar E, Guerrero G, Fernandez A, Molto E, Gonzalez-Buendia E, Cantero M, Montoliu L, Recillas-Targa F
Journal: Nucleic Acids Res - Page No (Thu Sep 02 00:00:00 EDT 2010)
Volume (Year): (2010)
Product Usage: -

Identification of mutations from phenotype-driven ENU mutagenesis in mouse chromosome 7.

Authors: Culiat CT, Klebig ML, Liu Z, Monroe H, Stanford B, Desai J, Tandan S, Hughes L, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Li Q
Journal: Mamm Genome - Page No 555 (Mon Aug 01 00:00:00 EDT 2005)
Volume (Year): 16 (2005)
Product Usage: -

Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice.

Authors: Sasaki R, Nishimura N, Hoshino H, Isa Y, Kadowaki M, Ichi T, Tanaka A, Nishiumi S, Fukuda I, Ashida H, Horio F, Tsuda T
Journal: Biochem Pharmacol - Page No 1619 (Mon Dec 03 00:00:00 EST 2007)
Volume (Year): 74 (2007)
Product Usage: -

Increased entropy production in diaphragm muscle of PPAR alpha knockout mice.

Authors: Lecarpentier Y, Krokidis X, Martin P, Pineau T, Hebert JL, Quillard J, Cortes-Morichetti M, Coirault C
Journal: J Theor Biol - Page No 92 (Mon Jan 07 00:00:00 EST 2008)
Volume (Year): 250 (2008)
Product Usage: -

Synaptic organization in cochlear inner hair cells deficient for the CaV1.3 (alpha1D) subunit of L-type Ca2+ channels.

Authors: Nemzou N RM, Bulankina AV, Khimich D, Giese A, Moser T
Journal: Neuroscience - Page No 1849 (Fri Sep 15 00:00:00 EDT 2006)
Volume (Year): 141 (2006)
Product Usage: -

Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization.

Authors: Kurz A, Wohr M, Walter M, Bonin M, Auburger G, Gispert S, Schwarting RK
Journal: Neuroscience - Page No 785 (Wed Mar 31 00:00:00 EDT 2010)
Volume (Year): 166 (2010)
Product Usage: -

Maturation of ribbon synapses in hair cells is driven by thyroid hormone.

Authors: Sendin G, Bulankina AV, Riedel D, Moser T
Journal: J Neurosci - Page No 3163 (Wed Mar 21 00:00:00 EDT 2007)
Volume (Year): 27 (2007)
Product Usage: -

The neuronal ceroid lipofuscinosis Cln8 gene expression is developmentally regulated in mouse brain and up-regulated in the hippocampal kindling model of epilepsy.

Authors: Lonka L, Aalto A, Kopra O, Kuronen M, Kokaia Z, Saarma M, Lehesjoki AE
Journal: Bmc Neurosci - Page No 27 (Sat Jan 01 00:00:00 EST 2005)
Volume (Year): 6 (2005)
Product Usage: -

Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.

Authors: Svec J, Ergang P, Mandys V, Kment M, Pacha J
Journal: Int J Exp Pathol - Page No 44 (Mon Feb 01 00:00:00 EST 2010)
Volume (Year): 91 (2010)
Product Usage: -

Protocatechuic acid induces antioxidant/detoxifying enzyme expression through JNK-mediated Nrf2 activation in murine macrophages.

Authors: Vari R, D'Archivio M, Filesi C, Carotenuto S, Scazzocchio B, Santangelo C, Giovannini C, Masella R
Journal: J Nutr Biochem - Page No (Fri Jul 09 00:00:00 EDT 2010)
Volume (Year): (2010)
Product Usage: -

Comparative analysis of the uterine and mammary gland effects of drospirenone and medroxyprogesterone acetate.

Authors: Otto C, Fuchs I, Altmann H, Klewer M, Walter A, Prelle K, Vonk R, Fritzemeier KH
Journal: Endocrinology - Page No 3952 (Fri Aug 01 00:00:00 EDT 2008)
Volume (Year): 149 (2008)
Product Usage: -

Corticosterone impairs dendritic cell maturation and function.

Authors: Elftman MD, Norbury CC, Bonneau RH, Truckenmiller ME
Journal: Immunology - Page No 279 (Mon Oct 01 00:00:00 EDT 2007)
Volume (Year): 122 (2007)
Product Usage: -

Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression.

Authors: Alavian KN, Sgado P, Alberi L, Subramaniam S, Simon HH
Journal: Neural Dev - Page No 11 (Thu Jan 01 00:00:00 EST 2009)
Volume (Year): 4 (2009)
Product Usage: -

Comparative in silico analysis identifies bona fide MyoD binding sites within the Myocyte stress 1 gene promoter.

Authors: Ounzain S, Dacwag CS, Samani NJ, Imbalzano AN, Chong NW
Journal: Bmc Mol Biol - Page No 50 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year): 9 (2008)
Product Usage: -

Attainment of brown adipocyte features in white adipocytes of hormone-sensitive lipase null mice.

Authors: Strom K, Hansson O, Lucas S, Nevsten P, Fernandez C, Klint C, Moverare-Skrtic S, Sundler F, Ohlsson C, Holm C
Journal: Plos One - Page No e1793 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year): 3 (2008)
Product Usage: -

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