Assay Details

Gene Symbol: Ppargc1a
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008904.2	NP_032930.1	5 - 6	890		104
RefSeq	NR_027710.1		5 - 6	890		104
GenBank mRNA	AB061324.1	-	5 - 6	813		104
	AF049330.1	-	5 - 6	842		104
	AK138668.1	-	5 - 6	891		104
	AK143753.1	-	5 - 6	842		104
	BC066868.1	-	5 - 6	785	30094033	104
	JX866948.1	-	5 - 6	778		104

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500002394.mm.1

Set Membership:

Ambion siRNA available

Amplicon length greater than or equal to 101

Mammalian Gene Collection

Mus musculus

Mouse Estrogen Panel

Inventoried

Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ppargc1a

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Function(s) Process(es)

Citations (13)

Sex-specific alterations in mRNA level of key lipid metabolism enzymes in skeletal muscle of overweight and obese subjects following endurance exercise.

Authors: Smith IJ, Huffman KM, Durheim MT, Duscha BD, Kraus WE
Journal: Physiol Genomics - Page No 149 (Mon Feb 02 00:00:00 EST 2009)
Volume (Year): 36 (2009)
Product Usage: -

SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD.

Authors: Amat R, Planavila A, Chen SL, Iglesias R, Giralt M, Villarroya F
Journal: J Biol Chem - Page No 21872 (Fri Aug 14 00:00:00 EDT 2009)
Volume (Year): 284 (2009)
Product Usage: -

Butyrate improves insulin sensitivity and increases energy expenditure in mice.

Authors: Gao Z, Yin J, Zhang J, Ward RE, Martin RJ, Lefevre M, Cefalu WT, Ye J
Journal: Diabetes - Page No 1509 (Wed Jul 01 00:00:00 EDT 2009)
Volume (Year): 58 (2009)
Product Usage: -

Parvalbumin deficiency and GABAergic dysfunction in mice lacking PGC-1alpha.

Authors: Lucas EK, Markwardt SJ, Gupta S, Meador-Woodruff JH, Lin JD, Overstreet-Wadiche L, Cowell RM
Journal: J Neurosci - Page No 7227 (Wed May 26 00:00:00 EDT 2010)
Volume (Year): 30 (2010)
Product Usage: -

Aging alters the expression of genes for neuroprotection and synaptic function following acute estradiol treatment.

Authors: Aenlle KK, Foster TC
Journal: Hippocampus - Page No 1047 (Wed Sep 01 00:00:00 EDT 2010)
Volume (Year): 20 (2010)
Product Usage: -

Fibroblast growth factor 21 corrects obesity in mice.

Authors: Coskun T, Bina HA, Schneider MA, Dunbar JD, Hu CC, Chen Y, Moller DE, Kharitonenkov A
Journal: Endocrinology - Page No 6018 (Mon Dec 01 00:00:00 EST 2008)
Volume (Year): 149 (2008)
Product Usage: -

Large-scale chemical dissection of mitochondrial function.

Authors: Wagner BK, Kitami T, Gilbert TJ, Peck D, Ramanathan A, Schreiber SL, Golub TR, Mootha VK
Journal: Nat Biotechnol - Page No 343 (Sat Mar 01 00:00:00 EST 2008)
Volume (Year): 26 (2008)
Product Usage: -

SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells.

Authors: Nasrin N, Wu X, Fortier E, Feng Y, Bare' OC, Chen S, Ren X, Wu Z, Streeper RS, Bordone L
Journal: J Biol Chem - Page No 31995 (Fri Oct 15 00:00:00 EDT 2010)
Volume (Year): 285 (2010)
Product Usage: -

Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice.

Authors: Pocai A, Carrington PE, Adams JR, Wright M, Eiermann G, Zhu L, Du X, Petrov A, Lassman ME, Jiang G, Liu F, Miller C, Tota LM, Zhou G, Zhang X, Sountis MM, Santoprete A, Capito' E, Chicchi GG, Thornberry N, Bianchi E, Pessi A, Marsh DJ, SinhaRoy R
Journal: Diabetes - Page No 2258 (Thu Oct 01 00:00:00 EDT 2009)
Volume (Year): 58 (2009)
Product Usage: -

The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity.

Authors: Lau P, Fitzsimmons RL, Raichur S, Wang SC, Lechtken A, Muscat GE
Journal: J Biol Chem - Page No 18411 (Fri Jun 27 00:00:00 EDT 2008)
Volume (Year): 283 (2008)
Product Usage: -

Requirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance.

Authors: Morel C, Standen CL, Jung DY, Gray S, Ong H, Flavell RA, Kim JK, Davis RJ
Journal: Mol Cell Biol - Page No 4616 (Fri Oct 01 00:00:00 EDT 2010)
Volume (Year): 30 (2010)
Product Usage: -

Nitric oxide and AMPK cooperatively regulate PGC-1 in skeletal muscle cells.

Authors: Lira VA, Brown DL, Lira AK, Kavazis AN, Soltow QA, Zeanah EH, Criswell DS
Journal: J Physiol - Page No 3551 (Wed Sep 15 00:00:00 EDT 2010)
Volume (Year): 588 (2010)
Product Usage: -

Attainment of brown adipocyte features in white adipocytes of hormone-sensitive lipase null mice.

Authors: Strom K, Hansson O, Lucas S, Nevsten P, Fernandez C, Klint C, Moverare-Skrtic S, Sundler F, Ohlsson C, Holm C
Journal: Plos One - Page No e1793 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year): 3 (2008)
Product Usage: -

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