Mm00448524_m1

• Gene Symbol: Pxn
• Gene Name: paxillin
• Gene Aliases: AW108311, AW123232, Pax
• Chromosome Location: Chr.5: 115506674 - 115555987 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pxn
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011223.3	NP_035353.1	1 - 2	194		93
	NM_133915.3	NP_598676.2	1 - 2	194		93
GenBank mRNA	AF293882.1	-	1 - 2	119		93
	AK148060.1	-	1 - 2	180		93
	AK149933.1	-	1 - 2	159		93
	AK167299.1	-	1 - 2	133		93
	AK171226.1	-	1 - 2	183		93
	AK171436.1	-	1 - 2	159		93
	BC025493.1	-	1 - 2	152		93

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500001264.mm.1

Additional Information:

This assay is in the 5'UTR region of the AF293882.1,AK148060.1,AK149933.1,AK167299.1,AK171436.1,NM_011223.3,NM_133915.3 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pxn

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

activation of MAPK activity
movement of cell or subcellular component
cytoskeleton organization
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
regulation of cell shape
peptidyl-tyrosine phosphorylation
lamellipodium assembly
substrate adhesion-dependent cell spreading
positive regulation of protein kinase activity
focal adhesion assembly
branching morphogenesis of an epithelial tube
growth hormone receptor signaling pathway

Function(s)

integrin binding
protein binding
beta-catenin binding
zinc ion binding
vinculin binding
protein kinase binding
receptor signaling complex scaffold activity
protein complex binding
metal ion binding
BH4 domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500010913.mm.1	TC0500001264.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500010913.mm.1	NM_011223.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010913.mm.1	NM_133915.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010902.mm.1	TC0500001264.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500010902.mm.1	NM_011223.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010902.mm.1	NM_133915.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010900.mm.1	TC0500001264.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500010900.mm.1	NM_011223.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010900.mm.1	NM_133915.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010903.mm.1	TC0500001264.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500010903.mm.1	NM_011223.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010903.mm.1	NM_133915.3	Refseq