Mm00448531_g1

• Gene Symbol: Pxn
• Gene Name: paxillin
• Gene Aliases: AW108311, AW123232, Pax
• Chromosome Location: Chr.5: 115506674 - 115555987 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pxn
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011223.3	NP_035353.1	8 - 9	1351		59
	NM_133915.3	NP_598676.2	9 - 10	1453		59
GenBank mRNA	AF293882.1	-	8 - 9	1276		59
	AF293883.1	-	8 - 9	1273		59
	AK148060.1	-	8 - 9	1337		59
	AK149933.1	-	8 - 9	1316		59
	AK167299.1	-	8 - 9	1290		59
	AK171226.1	-	8 - 9	1339		59
	BC003298.1	-	4 - 5	634		59
	BC025493.1	-	8 - 9	1309		59

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	AK089534.1	-				Chr. - - [-] on Build	59

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500001264.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pxn

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

activation of MAPK activity
movement of cell or subcellular component
cytoskeleton organization
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
regulation of cell shape
peptidyl-tyrosine phosphorylation
lamellipodium assembly
substrate adhesion-dependent cell spreading
positive regulation of protein kinase activity
focal adhesion assembly
branching morphogenesis of an epithelial tube
growth hormone receptor signaling pathway

Function(s)

integrin binding
protein binding
beta-catenin binding
zinc ion binding
vinculin binding
protein kinase binding
receptor signaling complex scaffold activity
protein complex binding
metal ion binding
BH4 domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500010935.mm.1	TC0500001264.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500010935.mm.1	NM_011223.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010935.mm.1	NM_133915.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010934.mm.1	TC0500001264.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500010934.mm.1	NM_011223.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500010934.mm.1	NM_133915.3	Refseq