Mm00449726_m1

• Gene Symbol: Sod2
• Gene Name: superoxide dismutase 2, mitochondrial
• Gene Aliases: MnSOD, Sod-2
• Chromosome Location: Chr.17: 13007839 - 13018119 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Sod2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_013671.3	NP_038699.2	2 - 3	433		67
GenBank mRNA	AK002428.1	-	2 - 3	293		67
	AK002534.1	-	2 - 3	294		67
	AK012354.1	-	2 - 3	291		67
	AK135435.1	-	2 - 3	422		67
	AK152047.1	-	2 - 3	291		67
	AK168082.1	-	2 - 3	294		67
	AK168591.1	-	2 - 3	425		67
	AK179113.1	-	1 - 2	53		67
	AK180974.1	-	1 - 2	53		67
	BC010548.1	-	2 - 3	269	3581909	67
	BC018173.1	-	1 - 2	214		67
	CT010273.1	-	2 - 3	226		67
	X04972.1	-	2 - 3	278		67
	Z18857.1	-	2 - 3	261		67

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700000148.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Mouse Alzheimer's Disease, Inventoried, Mouse_Alzheimer, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Sod2

Panther Classification:

Molecular Function -

oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
response to superoxide
age-dependent response to oxidative stress
age-dependent response to reactive oxygen species
release of cytochrome c from mitochondria
liver development
detection of oxygen
vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
regulation of transcription from RNA polymerase II promoter
glutathione metabolic process
superoxide metabolic process
response to oxidative stress
mitochondrion organization
heart development
sensory perception of sound
locomotory behavior
regulation of blood pressure
negative regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage
intrinsic apoptotic signaling pathway in response to oxidative stress
apoptotic mitochondrial changes
post-embryonic development
response to gamma radiation
response to activity
removal of superoxide radicals
respiratory electron transport chain
hemopoiesis
response to nutrient levels
oxygen homeostasis
vasodilation
response to drug
response to hydrogen peroxide
superoxide anion generation
hydrogen peroxide metabolic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of nitric oxide biosynthetic process
negative regulation of fat cell differentiation
negative regulation of fibroblast proliferation
neuron development
response to axon injury
erythrophore differentiation
hydrogen peroxide biosynthetic process
regulation of catalytic activity
protein homooligomerization
protein homotetramerization
regulation of mitochondrial membrane potential
iron ion homeostasis
response to hyperoxia
oxidation-reduction process
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Function(s)

DNA binding
superoxide dismutase activity
protein binding
oxidoreductase activity
oxygen binding
manganese ion binding
identical protein binding
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700001137.mm.1	NM_013671.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700001137.mm.1	NM_013671.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1700001137.mm.1	TC1700000148.mm.1	MTA TC