Mm00449859_m1

• Gene Symbol: Nbn
• Gene Name: nibrin
• Gene Aliases: Nbs1
• Chromosome Location: Chr.4: 15957967 - 15992589 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Nbn
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_013752.3	NP_038780.3	13 - 14	2176		109
GenBank mRNA	AB016988.1	-	13 - 14	2098		109
	AF076687.1	-	13 - 14	2170		109
	AF092840.1	-	13 - 14	2159		109
	AK132302.1	-	13 - 14	2218		109
	AK159790.1	-	13 - 14	2182		109
	AK160614.1	-	13 - 14	2143		109
	BC003719.1	-	13 - 14	2185		109
	BC055061.1	-	13 - 14	2168	6528890	109

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0400000140.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Nbn

Gene Ontology Categories:

Process(es)

DNA damage checkpoint signaling
telomere maintenance
in utero embryonic development
blastocyst growth
DNA repair
double-strand break repair
cellular response to DNA damage stimulus
cell cycle
mitotic cell cycle checkpoint signaling
mitotic G2 DNA damage checkpoint signaling
cell population proliferation
positive regulation of cell population proliferation
positive regulation of protein autophosphorylation
DNA duplex unwinding
positive regulation of kinase activity
isotype switching
negative regulation of neuron differentiation
negative regulation of viral entry into host cell
regulation of fibroblast proliferation
neuromuscular process controlling balance
meiotic cell cycle
intrinsic apoptotic signaling pathway

Function(s)

DNA helicase activity
damaged DNA binding
transcription factor binding
protein N-terminus binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0400000920.mm.1	TC0400000140.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0400000920.mm.1	NM_013752.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400000920.mm.1	NM_013752.3	Refseq