Mm00450592_m1

• Gene Symbol: Mre11a
• Gene Name: meiotic recombination 11 homolog A (S. cerevisiae)
• Gene Aliases: Mre11, Mre11b
• Chromosome Location: Chr.9: 14784670 - 14837125 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mre11a
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_018736.2	NP_061206.1	6 - 7	676		67
GenBank mRNA	AK041248.1	-	6 - 7	675		67
	AK141214.1	-	6 - 7	688		67
	AK146234.1	-	6 - 7	709		67
	AK146370.1	-	6 - 7	709		67
	AK168180.1	-	6 - 7	709		67
	AK168208.1	-	6 - 7	710		67
	BC065144.1	-	6 - 7	676	30627207	67
	U58987.1	-	6 - 7	711		67
	U60318.1	-	6 - 7	711		67

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0900000111.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Mre11a

Gene Ontology Categories:

Process(es)

telomere maintenance
DNA metabolic process
DNA repair
base-excision repair
double-strand break repair
double-strand break repair via nonhomologous end joining
cellular response to DNA damage stimulus
sister chromatid cohesion
mitotic G2 DNA damage checkpoint
synapsis
cell proliferation
intra-S DNA damage checkpoint
positive regulation of protein autophosphorylation
DNA duplex unwinding
negative regulation of DNA endoreduplication
positive regulation of kinase activity
negative regulation of viral entry into host cell
chromosome organization
meiotic cell cycle
nucleic acid phosphodiester bond hydrolysis

Function(s)

single-stranded DNA endodeoxyribonuclease activity
DNA binding
ATP-dependent DNA helicase activity
nuclease activity
endonuclease activity
endodeoxyribonuclease activity
exonuclease activity
protein C-terminus binding
3'-5' exonuclease activity
hydrolase activity
manganese ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0900000788.mm.1	NM_018736.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0900000788.mm.1	TC0900000111.mm.1	MTA TC