Mm00450596_m1

• Gene Symbol: Mre11a
• Gene Name: meiotic recombination 11 homolog A (S. cerevisiae)
• Gene Aliases: Mre11, Mre11b
• Chromosome Location: Chr.9: 14784670 - 14837125 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mre11a
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_018736.2	NP_061206.1	10 - 11	1223		124
GenBank mRNA	AK041248.1	-	10 - 11	1222		124
	AK141214.1	-	10 - 11	1235		124
	AK168208.1	-	10 - 11	1258		124
	BC065144.1	-	10 - 11	1223	30627207	124
	U58987.1	-	10 - 11	1258		124

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0900000111.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Mre11a

Gene Ontology Categories:

Process(es)

telomere maintenance
DNA metabolic process
DNA repair
base-excision repair
double-strand break repair
double-strand break repair via nonhomologous end joining
cellular response to DNA damage stimulus
sister chromatid cohesion
mitotic G2 DNA damage checkpoint
synapsis
cell proliferation
intra-S DNA damage checkpoint
positive regulation of protein autophosphorylation
DNA duplex unwinding
negative regulation of DNA endoreduplication
positive regulation of kinase activity
negative regulation of viral entry into host cell
chromosome organization
meiotic cell cycle
nucleic acid phosphodiester bond hydrolysis

Function(s)

single-stranded DNA endodeoxyribonuclease activity
DNA binding
ATP-dependent DNA helicase activity
nuclease activity
endonuclease activity
endodeoxyribonuclease activity
exonuclease activity
protein C-terminus binding
3'-5' exonuclease activity
hydrolase activity
manganese ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0900000794.mm.1	NM_018736.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0900000794.mm.1	TC0900000111.mm.1	MTA TC