Mm00469149_g1

• Gene Symbol: Ptpn6
• Gene Name: protein tyrosine phosphatase, non-receptor type 6
• Gene Aliases: 70Z-SHP, Hcph, PTPTY-42, Ptp1C, SH-PTP1, SHP-1, hcp, me
• Chromosome Location: Chr.6: 124720707 - 124738709 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ptpn6
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001077705.2	NP_001071173.1	5 - 6	834		59
	NM_013545.3	NP_038573.2	5 - 6	832		59
GenBank mRNA	AK132509.1	-	5 - 6	751		59
	AK150509.1	-	5 - 6	739		59
	AK151077.1	-	5 - 6	753		59
	AK151623.1	-	5 - 6	756		59
	AK159686.1	-	5 - 6	791		59
	AK159833.1	-	5 - 6	784		59
	AK167923.1	-	5 - 6	786		59
	AK169804.1	-	5 - 6	834		59
	M68902.1	-	5 - 6	784		59
	M90389.1	-	5 - 6	734		59

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0600003114.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Phosphatase, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ptpn6

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

hematopoietic progenitor cell differentiation
negative regulation of humoral immune response mediated by circulating immunoglobulin
protein dephosphorylation
signal transduction
cell proliferation
positive regulation of cell proliferation
positive regulation of phosphatidylinositol 3-kinase signaling
dephosphorylation
peptidyl-tyrosine phosphorylation
cytokine-mediated signaling pathway
cell differentiation
platelet formation
abortive mitotic cell cycle
positive regulation of cell adhesion mediated by integrin
peptidyl-tyrosine dephosphorylation
intracellular signal transduction
megakaryocyte development
negative regulation of T cell proliferation
natural killer cell mediated cytotoxicity
negative regulation of MAP kinase activity
negative regulation of MAPK cascade
regulation of B cell differentiation
negative regulation of peptidyl-tyrosine phosphorylation
B cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of T cell receptor signaling pathway
regulation of release of sequestered calcium ion into cytosol
regulation of ERK1 and ERK2 cascade
platelet aggregation
regulation of G1/S transition of mitotic cell cycle

Function(s)

phosphotyrosine binding
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
hydrolase activity
phosphatase activity
SH3 domain binding
protein kinase binding
SH2 domain binding
natural killer cell lectin-like receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0600024092.mm.1	TC0600003114.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0600024092.mm.1	NM_001077705.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0600024092.mm.1	NM_013545.3	Refseq