Mm00476362_m1

• Gene Symbol: Nfkb1
• Gene Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
• Gene Aliases: NF-KB1, NF-kappaB, NF-kappaB1, p105, p50, p50/p105
• Chromosome Location: Chr.3: 135584655 - 135691547 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Nfkb1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008689.2	NP_032715.2	7 - 8	901		90
GenBank mRNA	AB119195.1	-	5 - 6	399		90
	AB221614.1	-	5 - 6	406		90
	AK052726.1	-	2 - 3	209		90
	AY521462.1	-	5 - 6	399		90
	AY521463.1	-	5 - 6	399		90
	BC050841.1	-	7 - 8	901		90
	BC138535.1	-	6 - 7	478	8861555	90
	BC138536.1	-	6 - 7	478	8861556	90
	BC145317.1	-	7 - 8	495		90
	M57999.1	-	7 - 8	690		90

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0300002994.mm.1

Additional Information:

This assay is in the 5'UTR region of the AK052726.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Apoptosis, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Nfkb1

Panther Classification:

Molecular Function -

Rel homology transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
negative regulation of cytokine production
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
apoptotic process
inflammatory response
response to oxidative stress
signal transduction
I-kappaB kinase/NF-kappaB signaling
negative regulation of calcidiol 1-monooxygenase activity
response to cytokine
response to muscle stretch
NIK/NF-kappaB signaling
negative regulation of apoptotic process
negative regulation of interleukin-12 biosynthetic process
innate immune response
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
lymph node development
negative regulation of inflammatory response
cellular response to lipopolysaccharide
cellular response to nicotine
cellular response to interleukin-6
cellular response to dsRNA
cellular response to peptide hormone stimulus
positive regulation of canonical Wnt signaling pathway
positive regulation of hyaluronan biosynthetic process
positive regulation of miRNA metabolic process

Function(s)

regulatory region DNA binding
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
heat shock protein binding
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0300023640.mm.1	NM_008689.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300023640.mm.1	NM_008689.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0300023640.mm.1	TC0300002994.mm.1	MTA TC