Mm00488140_m1 Best Coverage

• Gene Symbol: Spi1
• Gene Name: spleen focus forming virus (SFFV) proviral integration oncogene
• Gene Aliases: Dis-1, Dis1, PU.1, Sfpi-1, Sfpi1, Spi-1, Tcfpu1, Tfpu.1
• Chromosome Location: Chr.2: 91082381 - 91115757 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Spi1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011355.1	NP_035485.1	1 - 2	194		82
GenBank mRNA	AK142246.1	-	1 - 2	211		82
	AK153524.1	-	1 - 2	225		82
	AK154945.1	-	1 - 2	246		82
	AK155085.1	-	1 - 2	230		82
	BC003815.1	-	1 - 2	112	3600260	82
	L03215.1	-	1 - 2	91		82
	M32370.1	-	1 - 2	174		82
	M38252.1	-	1 - 2	194		82
	X17463.1	-	1 - 2	882		82

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0200001368.mm.1

Additional Information:

This assay is in the 5'UTR region of the L03215.1,X17463.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Recommended Assay, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Spi1

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
vasculature development
lymphoid progenitor cell differentiation
myeloid leukocyte differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
lymphocyte differentiation
erythrocyte differentiation
macrophage differentiation
granulocyte differentiation
somatic stem cell population maintenance
myeloid dendritic cell differentiation
histone H3 acetylation
hypermethylation of CpG island
negative regulation of MHC class II biosynthetic process
regulation of erythrocyte differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anatomical structure regression
negative regulation of histone H4 acetylation
apoptotic process involved in patterning of blood vessels

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
RNA binding
protein binding
sequence-specific DNA binding
NFAT protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0200010517.mm.1	NM_011355.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0200010517.mm.1	TC0200001368.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0200010518.mm.1	NM_011355.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0200010518.mm.1	TC0200001368.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0200010520.mm.1	NM_011355.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0200010520.mm.1	TC0200001368.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	909012	-	-