Mm00488142_m1

• Gene Symbol: Spi1
• Gene Name: spleen focus forming virus (SFFV) proviral integration oncogene
• Gene Aliases: Dis-1, Dis1, PU.1, Sfpi-1, Sfpi1, Spi-1, Tcfpu1, Tfpu.1
• Chromosome Location: Chr.2: 91082381 - 91115757 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Spi1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011355.1	NP_035485.1	3 - 4	485		91
GenBank mRNA	AK142246.1	-	3 - 4	502		91
	AK153524.1	-	3 - 4	516		91
	AK154945.1	-	3 - 4	537		91
	AK155085.1	-	3 - 4	521		91
	BC003815.1	-	3 - 4	403	3600260	91
	L03215.1	-	3 - 4	382		91
	M32370.1	-	3 - 4	465		91
	M38252.1	-	3 - 4	485		91
	X17463.1	-	3 - 4	1173		91

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0200001368.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Spi1

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
vasculature development
lymphoid progenitor cell differentiation
myeloid leukocyte differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
lymphocyte differentiation
erythrocyte differentiation
macrophage differentiation
granulocyte differentiation
somatic stem cell population maintenance
myeloid dendritic cell differentiation
histone H3 acetylation
hypermethylation of CpG island
negative regulation of MHC class II biosynthetic process
regulation of erythrocyte differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anatomical structure regression
negative regulation of histone H4 acetylation
apoptotic process involved in patterning of blood vessels

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
RNA binding
protein binding
sequence-specific DNA binding
NFAT protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0200010523.mm.1	NM_011355.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0200010523.mm.1	TC0200001368.mm.1	MTA TC