Mm00488663_m1

• Gene Symbol: Map2k5
• Gene Name: mitogen-activated protein kinase kinase 5
• Gene Aliases: AI324775, AI428457, MEK5, Mapkk5, Prkmk5
• Chromosome Location: Chr.9: 63163768 - 63378438 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Map2k5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011840.2	NP_035970.1	15 - 16	1570		67
GenBank mRNA	AB019374.1	-	15 - 16	1571		67
	AK013856.1	-	7 - 8	413		67
	AK159261.1	-	15 - 16	1620		67
	BC028260.1	-	15 - 16	1450	5067818	67

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0900002472.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Map2k5

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
activation of MAPK activity
protein phosphorylation
heart development
phosphorylation
positive regulation of cell growth
negative regulation of NF-kappaB transcription factor activity
negative regulation of heterotypic cell-cell adhesion
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of interleukin-8 biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of epithelial cell proliferation
positive regulation of protein metabolic process
negative regulation of response to cytokine stimulus
ERK5 cascade
cellular response to growth factor stimulus
negative regulation of cell migration involved in sprouting angiogenesis
negative regulation of chemokine (C-X-C motif) ligand 2 production
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0900020700.mm.1	NM_011840.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900020700.mm.1	NM_011840.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900020700.mm.1	TC0900002472.mm.1	MTA TC