Mm00491036_g1

• Gene Symbol: Srf
• Gene Name: serum response factor
• Gene Aliases: AW049942, AW240594
• Chromosome Location: Chr.17: 46546838 - 46556870 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Srf
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_020493.2	NP_065239.1	5 - 6	1678		80
GenBank mRNA	BC051950.1	-	5 - 6	1691	6404515	80

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700002179.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Srf

Gene Ontology Categories:

Process(es)

patterning of blood vessels
in utero embryonic development
mesoderm formation
neuron migration
trophectodermal cell differentiation
heart looping
morphogenesis of an epithelial sheet
cell migration involved in sprouting angiogenesis
leukocyte differentiation
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
actin filament organization
cell-matrix adhesion
multicellular organism development
gastrulation
heart development
long-term memory
negative regulation of cell proliferation
associative learning
response to hormone
epithelial structure maintenance
positive regulation of transcription via serum response element binding
single organismal cell-cell adhesion
hippocampus development
tangential migration from the subventricular zone to the olfactory bulb
actin cytoskeleton organization
contractile actin filament bundle assembly
regulation of cell adhesion
platelet activation
platelet formation
negative regulation of cell migration
neuron projection development
regulation of water loss via skin
response to cytokine
megakaryocyte development
dorsal aorta morphogenesis
mRNA transcription from RNA polymerase II promoter
stress fiber assembly
skin morphogenesis
positive thymic T cell selection
sarcomere organization
positive regulation of cell differentiation
positive regulation of axon extension
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle contraction
positive regulation of transcription by glucose
muscle cell cellular homeostasis
developmental growth
erythrocyte development
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of filopodium assembly
cardiac myofibril assembly
hematopoietic stem cell differentiation
positive regulation of transcription initiation from RNA polymerase II promoter
long term synaptic depression
heart trabecula formation
lung morphogenesis
bronchus cartilage development
trachea cartilage development
cardiac vascular smooth muscle cell differentiation
eyelid development in camera-type eye
lung smooth muscle development
bicellular tight junction assembly
primitive streak formation
epithelial cell-cell adhesion
cellular senescence
negative regulation of beta-amyloid clearance

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
transcription factor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
serum response element binding
chromatin DNA binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
protein dimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700020548.mm.1	NM_020493.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020548.mm.1	NM_020493.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020548.mm.1	TC1700002179.mm.1	MTA TC