Mm00494255_m1

• Gene Symbol: Zap70
• Gene Name: zeta-chain (TCR) associated protein kinase
• Gene Aliases: Srk, ZAP-70, mrtle, mur
• Chromosome Location: Chr.1: 36761798 - 36782821 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Zap70
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001289765.1	NP_001276694.1	3 - 4	763		79
	NM_001289766.1	NP_001276695.1	3 - 4	728		79
	NM_009539.3	NP_033565.2	3 - 4	720		79
GenBank mRNA	AK039883.1	-	3 - 4	657		79
	AK089056.1	-	3 - 4	693		79
	BC029727.1	-	3 - 4	678	4925739	79
	U04379.1	-	3 - 4	674		79
	U77667.1	-	2 - 3	566		79

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0100000255.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protein Kinase, Mammalian Gene Collection, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Zap70

Gene Ontology Categories:

Process(es)

immune system process
protein phosphorylation
immune response
transmembrane receptor protein tyrosine kinase signaling pathway
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
cell differentiation
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
beta selection
positive thymic T cell selection
negative thymic T cell selection
thymic T cell selection
innate immune response
positive regulation of T cell differentiation
positive regulation of alpha-beta T cell differentiation
positive regulation of alpha-beta T cell proliferation
protein autophosphorylation
positive regulation of calcium-mediated signaling
T cell receptor signaling pathway

Function(s)

nucleotide binding
phosphotyrosine binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0100001724.mm.1	NM_001289765.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100001724.mm.1	NM_001289766.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100001724.mm.1	NM_009539.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0100001724.mm.1	TC0100000255.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0100001721.mm.1	NM_001289765.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100001721.mm.1	TC0100000255.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0100001723.mm.1	NM_001289765.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100001723.mm.1	NM_001289766.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100001723.mm.1	NM_009539.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0100001723.mm.1	TC0100000255.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0100001720.mm.1	NM_001289766.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100001720.mm.1	TC0100000255.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	613784	-	-