Mm00500167_m1

• Gene Symbol: Parp1
• Gene Name: poly (ADP-ribose) polymerase family, member 1
• Gene Aliases: 5830444G22Rik, AI893648, ARTD1, Adprp, Adprt1, C80510, PARP, PPOL, parp-1, sPARP-1
• Chromosome Location: Chr.1: 180568975 - 180601254 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Parp1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_007415.2	NP_031441.2	15 - 16	2215		63
GenBank mRNA	AK028042.1	-	15 - 16	2234		63
	AK030889.1	-	15 - 16	2218		63
	AK088679.1	-	15 - 16	2219		63
	AK146677.1	-	15 - 16	2236		63
	AK159433.1	-	15 - 16	2267		63
	AK165158.1	-	15 - 16	2235		63
	AK166104.1	-	15 - 16	2267		63
	AK167699.1	-	15 - 16	2207		63
	AK169326.1	-	15 - 16	2236		63
	BC012041.1	-	15 - 16	2215	2648390	63

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0100001711.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Parp1

Gene Ontology Categories:

Process(es)

telomere maintenance
DNA metabolic process
DNA repair
base-excision repair
double-strand break repair
transcription, DNA-templated
regulation of transcription, DNA-templated
protein ADP-ribosylation
cellular response to DNA damage stimulus
mitochondrion organization
transforming growth factor beta receptor signaling pathway
protein autoprocessing
signal transduction involved in regulation of gene expression
mitochondrial DNA metabolic process
cellular response to insulin stimulus
cellular response to oxidative stress
protein modification process
regulation of growth rate
DNA damage response, detection of DNA damage
mitochondrial DNA repair
positive regulation of transcription by RNA polymerase II
behavioral response to cocaine
positive regulation of SMAD protein signal transduction
protein poly-ADP-ribosylation
cellular response to superoxide
regulation of single strand break repair
positive regulation of transcription regulatory region DNA binding

Function(s)

DNA binding
chromatin binding
RNA binding
NAD+ ADP-ribosyltransferase activity
protein binding
transcription factor binding
zinc ion binding
transferase activity
glycosyltransferase activity
enzyme binding
protein kinase binding
identical protein binding
metal ion binding
protein N-terminus binding
NAD binding
R-SMAD binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0100014196.mm.1	TC0100001711.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0100014196.mm.1	NM_007415.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100014196.mm.1	NM_007415.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0100014197.mm.1	TC0100001711.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0100014197.mm.1	NM_007415.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100014197.mm.1	NM_007415.2	Refseq